Physical activity and circulating endothelial progenitor cells: An intervention study

Francesca Cesari, Francesco Sofi, Anna M. Gori, Ilaria Corsani, Andrea Capalbo, Roberto Caporale, Rosanna Abbate, Gian F. Gensini, Alessandro Casini

Research output: Contribution to journalArticlepeer-review


Background To assess the effect of a personalized physical activity programme on weight and circulating (CPC) and endothelial progenitor cells (EPC) in overweight and obese subjects. Materials and methods Anthropometric measurements with body composition, cardiopulmonary test, maximal stress exercise test with maximal oxygen uptake (VO2max) and a series of biochemical analyses were taken before (T0) and after 3months of physical activity (T1) in a total of 80 overweight and obese subjects. CPC and EPC were determined using flow cytometry and were defined as CD34+, CD133+ and CD34+/CD133+ for CPC and CD34+KDR+, CD133+KDR+ and CD34+CD133+KDR+ for EPC. Results At the end of the programme, we divided the population into two groups, compliant individuals (group A, n=47) and noncompliant individuals (group B, n=33). Group A reported significant reductions of weight by 3·1% (P

Original languageEnglish
Pages (from-to)927-932
Number of pages6
JournalEuropean Journal of Clinical Investigation
Issue number9
Publication statusPublished - Sep 2012


  • Endothelial progenitor cells
  • Obesity
  • Physical activity
  • Weight loss

ASJC Scopus subject areas

  • Medicine(all)
  • Clinical Biochemistry
  • Biochemistry


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