Physical activity and quality of cardiopulmonary resuscitation: A secondary analysis of the MANI-CPR trial

The MANI-CPR Investigators

Research output: Contribution to journalArticlepeer-review


Introduction: The association between the level of physical activity and quality of cardio-pulmonary resuscitation (CPR) performed by laypeople is unclear. The aim of this study was to evaluate the associations between physical activity level and laypeople performance during an eight-minute scenario of CPR. Materials and methods: This study was a secondary analysis of the MANI-CPR Trial. The entire cohort of participants was grouped based on the level of physical activity assessed using the International Physical Activity Questionnaire (IPAQ) into a “low-moderate” level group and a “high” level group. Descriptive statistics were used for unadjusted analysis and multivariate logistic and linear regression models were also performed. Results: A total of 492 participants who reached the score of “Advanced CPR performer” at the 1-min final test monitored by Laerdal Resusci Anne QCPR were included in this analysis; 224 with a low-moderate level and 268 with a high level of physical activity. A statistically significant difference was found for the outcome of percentage of compressions with adequate depth (low-moderate group: 87.8% [41·4%-99·3%], high group: 97% [63·2%–100%]; P = 0·003). No associations remained significant after controlling for biometric characteristics of the participants, compression protocols and sex. Conclusion: Adequate quality CPR may not need high baseline level of physical activity to be performed by a lay rescuer.

Original languageEnglish
Pages (from-to)330-334
Number of pages5
JournalAmerican Journal of Emergency Medicine
Publication statusPublished - Dec 2021


  • CPR
  • OHCA
  • Physical activity

ASJC Scopus subject areas

  • Emergency Medicine


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