Physical activity influences heart rate variability and very-low-frequency components in Holter electrocardiograms

Luciano Bernardi, Felice Valle, Michel Coco, Alessandro Calciati, Peter Sleight

Research output: Contribution to journalArticle

154 Citations (Scopus)

Abstract

Objective: A major proportion of RR interval variability in long-term recordings is due to slow (<0.03 Hz) fluctuations, which seem to be a good predictor of survival after myocardial infarction, whose origin remains unclear. Methods: To study the effect of physical activity we compared by spectral analysis of the RR interval in 10 healthy human subjects (aged 28[s.e. 2] years) during 1-h periods each of rest (no activity), alternating rest and mild exercise (rhythmic activity), and normal spontaneous (random) activity. Results: Compared to rest, during both random and rhythmic activities, the RR variance increased significantly (from 5802[1030] to 13388[1448] ms2, P <0.05, and to 24959[2901], P <0.001) due to an increase in power below 0.03 Hz (from 3017[467] to 9606[966] ms2, P <0.01, and to 21103[2298] ms2, P <0.001) which explained 55.4, 73.2 and 86.1% of total RR variance, respectively. Conclusions: The amount of RR variability and its slower fluctuations largely depend on physical activity, regardless of its regular or irregular occurrence. Attempts to predict cardiovascular prognosis on the basis of RR fluctuations should therefore take account of the confounding effect of physical activity since healthier subjects would probably be more active.

Original languageEnglish
Pages (from-to)234-237
Number of pages4
JournalCardiovascular Research
Volume32
Issue number2
DOIs
Publication statusPublished - Aug 1996

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Electrocardiography
Heart Rate
Exercise
Healthy Volunteers
Myocardial Infarction
Survival

Keywords

  • Autonomic nervous system
  • Exercise
  • Heart rate variability
  • Human
  • Spectral analysis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Physical activity influences heart rate variability and very-low-frequency components in Holter electrocardiograms. / Bernardi, Luciano; Valle, Felice; Coco, Michel; Calciati, Alessandro; Sleight, Peter.

In: Cardiovascular Research, Vol. 32, No. 2, 08.1996, p. 234-237.

Research output: Contribution to journalArticle

Bernardi, Luciano ; Valle, Felice ; Coco, Michel ; Calciati, Alessandro ; Sleight, Peter. / Physical activity influences heart rate variability and very-low-frequency components in Holter electrocardiograms. In: Cardiovascular Research. 1996 ; Vol. 32, No. 2. pp. 234-237.
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