Physical and biological characterizations of a novel multiphase anodic spark deposition coating to enhance implant osseointegration

Carmen Giordano, Roberto Chiesa, Enrico Sandrini, Alberto Cigada, Gianluca Giavaresi, Milena Fini, Roberto Giardino

Research output: Contribution to journalArticlepeer-review

Abstract

The present study assessed in vitro the short-term cellular response to surface physico-chemical properties of a new, purposed bioactive surface treatment called BioSpark™ performed on simply machined and on sand-blasted titanium. Material characterisation was carried out using scanning electron microscopy, energy dispersion spectroscopy, laser profilometry, and thin film X-ray diffraction. The in vitro biological study showed a suitable cellular response with adhesion and spreading level comparable for all the tested specimens. The proliferation analysis demonstrated that all the surfaces successfully supported cellular colonisation; in particular, higher cellular proliferation activity was observed on the BioSpark™-treated materials, with values higher than machined titanium. The results suggest that the BioSpark™ treatment represents a smart way to enhance osteoblastic cellular colonisation and thus improve osteointegration processes of machined and sandblasted titanium for orthopaedic and dental implants.

Original languageEnglish
Pages (from-to)1221-1229
Number of pages9
JournalJournal of Materials Science: Materials in Medicine
Volume16
Issue number12
DOIs
Publication statusPublished - Dec 2005

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Chemical Engineering(all)

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