Physical performance measures and hospital outcomes among Italian older adults: results from the CRIME project

Emanuele Rocco Villani, Davide Liborio Vetrano, Laura Franza, Angelo Carfì, Vincenzo Brandi, Stefano Volpato, Andrea Corsonello, Fabrizia Lattanzio, Carmelinda Ruggiero, Graziano Onder, Katie Palmer

Research output: Contribution to journalArticlepeer-review


Background: Older adults are a complex population, at risk of adverse events during and after hospital stay. Aim: To investigate the association of walking speed (WS) and grip strength (GS) with adverse outcomes, during and after hospitalization, among older individuals admitted to acute care wards. Methods: Multicentre observational study including 1123 adults aged ≥ 65 years admitted to acute wards in Italy. WS and GS were measured at admission and discharge. Outcomes were length-of-stay, in-hospital mortality, 1-year mortality and rehospitalisation. Length-of-stay was defined as a number of days from admission to discharge/death. Results: Mean age was 81 ± 7 years, 56% were women. Compared to patients with WS ≥ 0.8 m/sec, those unable to perform or with WS < 0.8 m/sec had a higher likelihood of longer length-of-stay (OR 2.57; 95% CI 1.63–4.03 and 2.42; 95% CI 1.55–3.79) and 1-year mortality and rehospitalization (OR 1.47, 95% CI 1.07–2.01; OR 1.57, 95% CI 1.04–2.37); those unable to perform WS had a higher likelihood of in-hospital mortality (OR 9.59; 95% CI 1.23–14.57) and 1-year mortality (OR 2.60; 95% CI 1.37–4.93). Compared to good GS performers, those unable to perform had a higher likelihood of in-hospital mortality (OR 17.43; 95% CI 3.87–28.46), 1-year mortality (OR 3.14; 95% CI 1.37–4.93) and combination of 1-year mortality and rehospitalisation (OR 1.46; 95% CI 1.01–2.12); poor GS performers had a higher likelihood of 1-year mortality (OR 1.39; 95% CI 1.03–2.35); participants unable to perform GS had a lower likelihood of rehospitalisation (OR 0.59; 95% CI 0.39–0.89). Conclusion: Walking speed (WS) and grip strength (GS) are easy-to-assess predictors of length-of-stay, in-hospital and post-discharge death and should be incorporated in the standard assessment of hospitalized patients.

Original languageEnglish
JournalAging clinical and experimental research
Publication statusE-pub ahead of print - 2020


  • Acute care
  • Adverse health outcomes
  • Aging
  • Elderly
  • Grip strength
  • Walking speed

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

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