Physically enhanced coating of a titanium plasma-spray surface with human SAOS-2 osteoblasts and extracellular matrix

Lorenzo Fassina; Enrica Saino; Livia Visai; Giovanni Magenes

doi:10.1109/IEMBS.2007.4353824

Physically enhanced coating of a titanium plasma-spray surface with human SAOS-2 osteoblasts and extracellular matrix

Lorenzo Fassina, Enrica Saino, Livia Visai, Giovanni Magenes

Istituti Clinici Scientifici Maugeri Spa – Società Benefit

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Several studies suggest that the modification of a titanium surface could play an important role in bone tissue engineering. In this study we have followed a biomimetic strategy where ultrasonically or electromagnetically stimulated human SAOS-2 osteoblasts proliferated and built their extracellular matrix on a titanium plasma-spray surface. In comparison with control conditions, the ultrasonic stimulus (power, 149 mW; frequency, 1.5 MHz) and the electromagnetic stimulus (magnetic field, 2 mT; frequency, 75 Hz) increased the cell proliferation and the surface coating with type-I collagen. The physical stimuli aimed at obtaining a better modification of the rough titanium plasma-spray surface in terms of cell colonization and coating with bone matrix. The superficially modified biomaterial could be used, in clinical applications, as an implant for bone repair.

Original language	English
Title of host publication	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages	6414-6417
Number of pages	4
DOIs	https://doi.org/10.1109/IEMBS.2007.4353824
Publication status	Published - 2007
Event	29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France Duration: Aug 23 2007 → Aug 26 2007

Other

Other	29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
Country	France
City	Lyon
Period	8/23/07 → 8/26/07

ASJC Scopus subject areas

Biomedical Engineering

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Fassina, L., Saino, E., Visai, L., & Magenes, G. (2007). Physically enhanced coating of a titanium plasma-spray surface with human SAOS-2 osteoblasts and extracellular matrix. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 6414-6417). [4353824] https://doi.org/10.1109/IEMBS.2007.4353824

Physically enhanced coating of a titanium plasma-spray surface with human SAOS-2 osteoblasts and extracellular matrix. / Fassina, Lorenzo; Saino, Enrica; Visai, Livia; Magenes, Giovanni.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2007. p. 6414-6417 4353824.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Fassina, L, Saino, E, Visai, L & Magenes, G 2007, Physically enhanced coating of a titanium plasma-spray surface with human SAOS-2 osteoblasts and extracellular matrix. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings., 4353824, pp. 6414-6417, 29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07, Lyon, France, 8/23/07. https://doi.org/10.1109/IEMBS.2007.4353824

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