Physically enhanced coating of a titanium plasma-spray surface with human SAOS-2 osteoblasts and extracellular matrix

Lorenzo Fassina, Enrica Saino, Livia Visai, Giovanni Magenes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Several studies suggest that the modification of a titanium surface could play an important role in bone tissue engineering. In this study we have followed a biomimetic strategy where ultrasonically or electromagnetically stimulated human SAOS-2 osteoblasts proliferated and built their extracellular matrix on a titanium plasma-spray surface. In comparison with control conditions, the ultrasonic stimulus (power, 149 mW; frequency, 1.5 MHz) and the electromagnetic stimulus (magnetic field, 2 mT; frequency, 75 Hz) increased the cell proliferation and the surface coating with type-I collagen. The physical stimuli aimed at obtaining a better modification of the rough titanium plasma-spray surface in terms of cell colonization and coating with bone matrix. The superficially modified biomaterial could be used, in clinical applications, as an implant for bone repair.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages6414-6417
Number of pages4
DOIs
Publication statusPublished - 2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07 - Lyon, France
Duration: Aug 23 2007Aug 26 2007

Other

Other29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society, EMBC'07
CountryFrance
CityLyon
Period8/23/078/26/07

ASJC Scopus subject areas

  • Biomedical Engineering

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    Fassina, L., Saino, E., Visai, L., & Magenes, G. (2007). Physically enhanced coating of a titanium plasma-spray surface with human SAOS-2 osteoblasts and extracellular matrix. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (pp. 6414-6417). [4353824] https://doi.org/10.1109/IEMBS.2007.4353824