Abstract
| Original language | English |
|---|---|
| Journal | Front. Oncol. |
| Volume | 10 |
| DOIs | |
| Publication status | Published - 2020 |
Keywords
- alternative medicine
- attitudes
- cancer
- complementary medicine
- Italian survey
- physicians
- treatment
- ascorbic acid
- acupuncture
- adult
- aged
- allopathy
- Aloe vera
- Article
- cancer patient
- chronic disease
- controlled study
- cross-sectional study
- female
- human
- internal medicine
- Italy
- male
- medical specialist
- oncology
- perception
- physician attitude
- questionnaire
- radiotherapy
- surgery
- work experience
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Physician Attitudes and Perceptions of Complementary and Alternative Medicine (CAM): A Multicentre Italian Study : Frontiers in Oncology. / Berretta, M.; Rinaldi, L.; Taibi, R.; Tralongo, P.; Fulvi, A.; Montesarchio, V.; Madeddu, G.; Magistri, P.; Bimonte, S.; Trovò, M.; Gnagnarella, P.; Cuomo, A.; Cascella, M.; Lleshi, A.; Nasti, G.; Facchini, S.; Fiorica, F.; Di Francia, R.; Nunnari, G.; Pellicanò, G.F.; Guglielmino, A.; Danova, M.; Rossetti, S.; Amore, A.; Crispo, A.; Facchini, G.
In: Front. Oncol., Vol. 10, 2020.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Physician Attitudes and Perceptions of Complementary and Alternative Medicine (CAM): A Multicentre Italian Study
T2 - Frontiers in Oncology
AU - Berretta, M.
AU - Rinaldi, L.
AU - Taibi, R.
AU - Tralongo, P.
AU - Fulvi, A.
AU - Montesarchio, V.
AU - Madeddu, G.
AU - Magistri, P.
AU - Bimonte, S.
AU - Trovò, M.
AU - Gnagnarella, P.
AU - Cuomo, A.
AU - Cascella, M.
AU - Lleshi, A.
AU - Nasti, G.
AU - Facchini, S.
AU - Fiorica, F.
AU - Di Francia, R.
AU - Nunnari, G.
AU - Pellicanò, G.F.
AU - Guglielmino, A.
AU - Danova, M.
AU - Rossetti, S.
AU - Amore, A.
AU - Crispo, A.
AU - Facchini, G.
N1 - Cited By :1 Export Date: 1 March 2021 Correspondence Address: Berretta, M.; Department of Medical Oncology, Italy; email: mberretta@cro.it Chemicals/CAS: ascorbic acid, 134-03-2, 15421-15-5, 50-81-7 Funding text 1: The authors are grateful to Gianpiero Guerrini, MD (University of Modena and Reggio Emilia, Modena, Italy) and Daniele Bernardi, MD (Division of Medical Oncology, San Don? Hospital, San Don?, Italy) for support to the cases and to all the physicians who participated in the survey. The authors acknowledge Word Designs (www.silviamodena.com) for editorial assistance. References: https://nccih.nih.gov/health/integrative-health, Available online at:, (accessed April 16, 2020; Hyodo, I., Eguchi, K., Nishina, T., Endo, H., Tanimizu, M., Mikami, I., Perceptions and attitudes of clinical oncologists on complementary and alternative medicine: a nationwide survey in Japan (2003) Cancer, 97, pp. 2861-2868; Eisenberg, D.M., Davis, R.B., Ettner, S.L., Appel, S., Wilkey, S., Van Rompay, M., Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey (1998) JAMA, 280, pp. 1569-1575. , 9820257; Abou-Rizk, J., Alameddine, M., Naja, F., Prevalence and characteristics of CAM Use among people living with HIV and AIDS in Lebanon: implications for patient care (2016) Evid Based Complement Alternat Med, 2016, p. 5013132. , 28050191; Dehghan, M., Ghaedi Heidari, F., Malakoutikhah, A., Mokhtarabadi, S., Complementary and alternative medicine usage and its determinant factors among Iranian patients with cancer (2019) WCRJ, 6, p. e1382; (2001) A Collection of Papers Prepared for Health Canada, , Ottawa, ON, Health Canada; Berretta, M., Della Pepa, C., Tralongo, P., Fulvi, A., Martellotta, F., Lleshi, A., Use of complementary and alternative medicine (CAM) in cancer patients: an Italian multicenter survey (2017) Oncotarget, 8, pp. 24401-24414. , 28212560; Fisher, P., Ward, A., Complementary medicine in Europe (1994) BMJ, 309, pp. 107-111. , 8038643; (1998) Report: Technical Briefing on Traditional Medicine. Presented at the Forty-Ninth Regional Office for the Western Pacific, , Geneva; Sparreboom, A., Cox, M.C., Acharya, M.R., Figg, W.D., Herbal remedies in the United States: potential adverse interactions with anticancer agents (2004) J Clin Oncol, 22, pp. 2489-2503; Frye, R.F., Fitzgerald, S.M., Lagattuta, T.F., Hruska, M.W., Egorin, M.J., Effect of St John's wort on imatinib mesylate pharmacokinetics (2004) Clin Pharmacol Ther, 76, pp. 323-329; Golden, E.B., Lam, P.Y., Kardosh, A., Gaffney, K.J., Cadenas, E., Louie, S.G., Green tea polyphenols block the anticancer effects of bortezomib and other boronic acid-based proteasome inhibitors (2009) Blood, 113, pp. 5927-5937. , 19190249; Mazzanti, G., Menniti-Ippolito, F., Moro, P.A., Cassetti, F., Raschetti, R., Santuccio, C., Hepatotoxicity from green tea: a review of the literature and two unpublished cases (2009) Eur J Clin Pharmacol, 65, pp. 331-341. , 19198822; McCune, J.S., Hatfield, A.J., Blackburn, A.A., Leith, P.O., Livingston, R.B., Ellis, G.K., Potential of chemotherapy-herb interactions in adult cancer patients (2004) Support Care Cancer, 12, pp. 454-462. , 14991387; D'Orta, A., Del Buono, A., De Monaco, A., Zhiqiang, P., Licito, A., Di Martino, S., Management and treatment of sarcopenia in fifty patients receiving chemotherapy with AHCC (active hexose correlated compound) (2018) WCRJ, 5, p. e1089. , https://www.wcrj.net/article/1089, Available online at; Bhui, K., Tyagi, S., Prakash, B., Shukla, Y., Pineapple bromelain induces autophagy, facilitating apoptotic response in mammary carcinoma cells (2010) Biofactors, 36, pp. 474-482. , 20848558; Schuurman, A.G., Goldbohm, R.A., Brants, H.A., van den Brandt, P.A., A prospective cohort study on intake of retinol, vitamins C and E, and carotenoids and prostate cancer risk (Netherlands) (2002) Cancer Causes Control, 13, pp. 573-582. , 12195647; Li, Q.Q., Wang, G., Zhang, M., Cuff, C.F., Huang, L., Reed, E., βeta-Elemene, a novel plant-derived antineoplastic agent, increases cisplatin chemosensitivity of lung tumor cells by triggering apoptosis (2009) Oncol Rep, 22, pp. 161-170; Pitchakarn, P., Ohnuma, S., Pintha, K., Pompimon, W., Ambudkar, S.V., Limtrakul, P., Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance (2012) J Nutr Biochem, 23, pp. 76-78. , 21414769; Sanmukhani, J., Satodia, V., Trivedi, J., Patel, T., Tiwari, D., Panchal, B., Efficacy and safety of curcumin in major depressive disorder: a randomized controlled trial (2014) Phytother Res, 28, pp. 579-585. , 23832433; Scott, K.A., Dalgleish, A.G., Liu, W.M., Anticancer effects of phytocannabinoids used with chemotherapy in leukaemia cells can be improved by altering the sequence of their administration (2017) Int J Oncol, 51, pp. 369-377. , 28560402; Todisco, M., Casaccia, P., Rossi, N., Cyclophosphamide plus somatostatin, bromocriptine, retinoids, melatonin and ACTH in the treatment of low-grade non-Hodgkin's lymphomas at advanced stage: results of a phase II trial (2001) Cancer Biother Radiopharm, 16, pp. 171-177; Liatsos, G., Elefsiniotis, I., Todorova, R., Moulakakis, A., Severe thrombotic thrombocytopenic purpura (TTP) induced or exacerbated by the immunostimulatory herb Echinacea (2006) Am J Hematol, 81, p. 224. , 16493617; Eberding, A., Madera, C., Xie, S., Wood, C.A., Brown, P.N., Guns, E.S., Evaluation of the antiproliferative effects of Essiac on in vitro and in vivo models of prostate cancer compared to paclitaxel (2007) Nutr Cancer, 58, pp. 188-196; Qin, X., Cui, Y., Shen, L., Sun, N., Zhang, Y., Li, J., Folic acid supplementation and cancer risk: a meta-analysis of randomized controlled trials (2013) Int J Cancer, 133, pp. 1033-1041. , 23338728; Rossi, P., Difrancia, R., Quagliariello, V., Savino, E., Tralongo, P., Randazzo, C.L., B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine (2018) Oncotarget, 9, pp. 24837-24856. , 29872510; Engdal, S., Nilsen, O.G., In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients (2009) Phytother Res, 23, pp. 906-912. , 19170155; Park, Y.J., Choo, W.H., Kim, H.R., Chung, K.H., Oh, S.M., Inhibitory aromatase effects of flavonoids from ginkgo biloba extracts on estrogen biosynthesis (2015) Asian Pac J Cancer Prev, 16, pp. 6317-6325. , 26434836; Bilgi, N., Bell, K., Ananthakrishnan, A.N., Atallah, E., Imatinib and Panax ginseng: a potential interaction resulting in liver toxicity (2010) Ann Pharmacother, 44, pp. 926-928; Katayanagi, S., Katsumata, K., Mori, Y., Narahara, K., Shigoka, M., Matsudo, T., GSTP1 as a potential predictive factor for adverse events associated with platinum-based antitumor agent-induced peripheral neuropathy (2019) Oncol Lett, 17, pp. 2897-2904. , 30854066; Naing, A., Aaron, J., Kurzrock, R., Juice plus or toxicity plus (2010) Am J Med, 123, pp. e1-e2; Li, G., Simmler, C., Chen, L., Nikolic, D., Chen, S.N., Pauli, G.F., Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents (2017) Eur J Pharm Sci, 109, pp. 182-190. , 28774812; Zhang, Y., Ge, Y., Ping, X., Yu, M., Lou, D., Shi, W., Synergistic apoptotic effects of silibinin in enhancing paclitaxel toxicity in human gastric cancer cell lines (2018) Mol Med Rep, 18, pp. 1835-1841. , 29901126; Pan, Y., Rhea, P., Tan, L., Cartwright, C., Lee, H.J., Ravoori, M.K., PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway (2014) Invest New Drugs, 33, pp. 271-279; Daenen, L.G.M., Cirkel, G.A., Houthuijzen, M., Gerrits, J., Oosterom, I., Roodhart, J.M.L., Increased plasma levels of chemoresistance-inducing fatty acid 16:4(n-3) after consumption of fish and fish oil (2015) JAMA Oncol, 1, pp. 350-358; Clavo, B., Santana-Rodríguez, N., Llontop, P., Gutiérrez, D., Suárez, G., López, L., Ozone therapy as adjuvant for cancer treatment: is further research warranted? (2018) Evid Based Complement Alternat Med, 2018, p. 7931849. , 30271455; Parvaresh, A., Razavi, R., Rafie, N., Ghiasvand, R., Pourmasoumi, M., Miraghajani, M., Quercetin and ovarian cancer: an evaluation based on a systematic review (2016) J Res Med Sci, 21, p. 34. , 27904580; Zhang, C., Feng, Y., Qu, S., Wei, X., Zhu, H., Luo, Q., Resveratrol attenuates doxorubicin-induced cardiomyocyte apoptosis in mice through SIRT1-mediated deacetylation of p53 (2011) Cardiovasc Res, 90, pp. 538-545. , 21278141; Savranoglu, S., Tumer, T.B., Inhibitory effects of spirulina platensis on carcinogen-activating cytochrome P450 isozymes and potential for drug interactions (2013) Int J Toxicol, 32, pp. 376-384. , 24082030; Chang, Y., Wang, S.J., Hypericin, the active component of St (2010) Eur J Pharmacol, 634, pp. 53-61. , 20193678, John's wort, inhibits glutamate release the rat cerebrocortical synaptosomes via a mitogen-activated protein kinase-dependent pathway; Ullah, M.F., Khan, H.Y., Zubair, H., Shamim, U., Hadi, S.M., The antioxidant ascorbic acid mobilizes nuclear copper leading to a prooxidant breakage of cellular DNA: implications for chemotherapeutic action against cancer (2011) Cancer Chemother Pharmacol, 67, pp. 103-110. , 20213077; Pellegrino, P., Mallet, B., Delliaux, S., Jammes, Y., Guieu, R., Schäf, O., Zeolites are effective ROS-scavengers in vitro (2011) Biochem Biophys Res Commun, 410, pp. 478-483. , 21679693; Brown, P.R., Alaszewski, A., Swift, T., Nordin, A., Actions speak louder than words: the embodiment of trust by healthcare professionals in gynae-oncology (2011) Sociol Health Illn, 33, pp. 280-295. , 21299570; Musselmann, B., Szecsenyi, J., Joos, S., Complementary and alternative medicine in practice - the diagnostic-therapeutic process from the perspective of general practitioners: a qualitative study (2009) Forsch Komplementmed, 16, pp. 392-399. , 20090352; Richardson, M.A., Mâsse, L.C., Nanny, K., Sanders, C., Discrepant views of oncologists and cancer patients on complementary/alternative medicine (2004) Support Care Cancer, 12, pp. 797-804. , 15378417; Richardson, M.A., Sanders, T., Palmer, J.L., Greisinger, A., Singletary, S.E., Complementary/alternative medicine use in a comprehensive cancer center and the implications for oncology (2000) J Clin Oncol, 18, pp. 2505-2514. , 10893280; Crocetti, E., Crotti, N., Montella, M., Musso, M., Complementary medicine and oncologists' attitudes: a survey in Italy (1996) Tumori, 82, pp. 539-542. , 9061060; Italians and 'Dr. Google': almost nine million are victims of fake news on medications (Italian) 13th December 2017, , http://www.dire.it/13–12-2017/160084-gli-italiani-e-il-dottor-google-quasi-nove-ilionisono-vittima-di-fake-news-sui-farmaci/, Available online at:, (accessed March 12, 2019; Breslow, N.E., Day, N.E., Statistical methods in cancer research (1980) IARC Sci Publ, 1, pp. 5-338. , ume I - The analysis of case-control studies; Kretchy, I.A., Okere, H.A., Osafo, J., Afrane, B., Sarkodie, J., Debrah, P., Perceptions of traditional, complementary and alternative medicine among conventional healthcare practitioners in Accra, Ghana: implications for integrative healthcare (2016) J Integr Med, 14, pp. 380-388. , 27641609; Fischer, F.H., Lewith, G., Witt, C.M., Linde, K., von Ammon, K., Cardini, F., High prevalence but limited evidence in complementary and alternative medicine: guidelines for future research (2014) BMC Complement Altern Med, 14, p. 46. , 24499316; Ben-Arye, E., Frenkel, M., Klein, A., Scharf, M., Attitudes toward integration of complementary and alternative medicine in primary care: perspectives of patients, physicians and complementary practitioners (2008) Patient Educ Couns, 70, pp. 395-402. , 18201857; Deng, G., Cassileth, B., Integrative oncology: an overview (2014) Am Soc Clin Oncol Educ Book, pp. 233-242. , 24857081; Muecke, R., Paul, M., Conrad, C., Stoll, C., Muenstedt, K., Micke, O., Complementary and alternative medicine in palliative care: a comparison of data from surveys among patients and professionals (2016) Integr Cancer Ther, 15, pp. 10-16. , 26721796; Wetzel, M.S., Kaptchuk, T.J., Haramati, A., Eisenberg, D.M., Complementary and alternative medical therapies: implications for medical education (2003) Ann Intern Med, 138, pp. 191-196. , 12558358; Hunter, J., Ussher, J., Parton, C., Kellett, A., Smith, C., Delaney, G., Australian integrative oncology services: a mixed-method study exploring the views of cancer survivors (2018) BMC Complement Altern Med, 18, p. 153; Lim, E., Vardy, J.L., Oh, B., Dhillon, H.M., Comparison of integrative medicine centers in the USA and Germany: a mixed method study (2017) Support Care Cancer, 25, pp. 1865-1872. , 28124123; Jansen, E., the role of complementary and alternative medicine in the healthcare system: a German paradox (2017) Complement Med Res, 24, pp. 290-294. , 28934737; Weeks, L.C., Seely, D., Balneaves, L.G., Boon, H.S., Leis, A., Oneschuk, D., Canadian integrative oncology research priorities: results of a consensus-building process (2013) Curr Oncol, 20, pp. e289-e299. , 23904767; Yang, G., Lee, R., Zhang, H., Gu, W., Yang, P., Ling, C., National survey of China's oncologists' knowledge, attitudes, and clinical practice patterns on complementary and alternative medicine (2017) Oncotarget, 8, pp. 13440-13449. , 28088780; Stub, T., Salamonsen, A., Kristoffersen, A., Musial, F., How to handle worsening of condition during treatment - risk assessment in homeopathic practice (2015) Forsch Komplementmed, 22, pp. 30-35; Salamonsen, A., Doctor-patient communication and cancer patients' choice of alternative therapies as supplement or alternative to conventional care (2013) Scand J Caring Sci, 27, pp. 70-76; Kooreman, P., Baars, E.W., Patients whose GP knows complementary medicine tend to have lower costs and live longer (2012) Eur J Health Econ, 13, pp. 769-776. , 21695547; Lee, R.T., Hlubocky, F.J., Hu, J.J., Stafford, R.S., Daugherty, C.K., An international pilot study of oncology physicians' opinions and practices on complementary and alternative medicine (CAM) (2008) Integr Cancer Ther, 7, pp. 70-75. , 18505899; Cassileth, B.R., Complementary and alternative cancer medicine (1999) J Clin Oncol, 17, pp. 44-52. , 10630262; Jacobson, J.S., Workman, S.B., Kronenberg, F., Research on complementary/alternative medicine for patients with breast cancer: a review of the biomedical literature (2000) J Clin Oncol, 18, pp. 668-683. , 10653883; Conrad, A.C., Muenstedt, K., Micke, O., Prott, F.J., Muecke, R., Huebner, J., Attitudes of members of the German Society for palliative medicine toward complementary and alternative medicine for cancer patients (2014) J Cancer Res Clin Oncol, 140, pp. 1229-1237. , 24706260; Ott, I.M., Münstedt, K., Micke, O., Mücke, R., Prott, F.J., Senf, B., Attitude of oncology/haematology nurses from German speaking countries towards complementary and alternative medicine (2015) Trace Elem Electroly, 32, pp. 74-80; Trimborn, A., Senf, B., Muenstedt, K., Buentzel, J., Micke, O., Muecke, R., Attitude of employees of a university clinic to complementary and alternative medicine in oncology (2013) Ann Oncol, 24, pp. 2641-2645. , 23942776; Cassileth, B.R., Lusk, E.J., Strouse, T.B., Bodenheimer, B.J., Contemporary unorthodox treatments in cancer medicine (1984) Ann Intern Med, 101, pp. 105-112. , 6732073, a study of patients, treatments, and practitioners; Wetzel, M.S., Eisenberg, D.M., Kaptchuk, T.J., Courses involving complementary and alternative medicine at US medical schools (1998) JAMA, 280, pp. 784-787. , 9729989; Hamouda, O., Sweilam, M., Abdellah, A., El Sayed, S.M., Evaluation of pioneering introduction of integrative and prophetic medicine education in an Arabic medical school (Taibah University, Saudi Arabia): 10 years' experience (2019) J Int Med Res, 47, pp. 2157-2165. , 30966841; Johnson, S.B., Park, H.S., Gross, C.P., Yu, J.B., Use of alternative medicine for cancer and its impact on survival (2018) J Natl cancer Inst, 110, p. djx145. , 28922780; Engdal, S., Klepp, O., Nilsen, O.G., Identification and exploration of herb-drug combinations used by cancer patients (2009) Integr Cancer Ther, 8, pp. 29-36; Loquai, C., Dechent, D., Garzarolli, M., Kaatz, M., Kaehler, K.C., Kurschat, P., Risk of interactions between complementary and alternative medicine and medication for comorbidities in patients with melanoma (2016) Med Oncol, 33, p. 52. , 27090799; Motoo, Y., Yukawa, K., Hisamura, K., Tsutani, K., Arai, I., Internet survey on the provision of complementary and alternative medicine in Japanese private clinics: a cross-sectional study (2019) J Integr Med, 17, pp. 8-13. , 30482472; Farooqui, M., Othman, C.N., Hassali, A.A., Saleem, F., Ul Haq, N., Sadeeqa, S., A qualitative exploration of Malaysian doctors' perceptions towards complementary and alternative medicines (Cam) (2014) Value Health, 17, p. A789. , 27202944; Quagliariello, V., Iaffaioli, R.V., Armenia, E., Clemente, O., Barbarisi, M., Nasti, G., Hyaluronic acid nanohydrogel loaded with quercetin alone or in combination to a macrolide derivative of Rapamycin RAD001 (Everolimus) as a new treatment for hormone-responsive human breast cancer (2017) J Cell Physiol, 232, pp. 2063-2074. , 27607841; Barbieri, A., Quagliariello, V., Del Vecchio, V., Falco, M., Luciano, A., Amruthraj, N.J., Anticancer and anti-inflammatory properties of ganoderma lucidum extract effects on melanoma and triple-negative breast cancer treatment (2017) Nutrients, 9, p. E210. , 28264501; Loganathan, J., Jiang, J., Smith, A., Jedinak, A., Thyagarajan-Sahu, A., Sandusky, G.E., The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes (2014) Int J Oncol, 44, pp. 2009-2015. , 24718855; Tirelli, U., Cirrito, C., Pavanello, M., Del Pup, L., Lleshi, A., Berretta, M., Oxygen-ozone therapy as support and palliative therapy in 50 cancer patients with fatigue - A short report (2018) Eur Rev Med Pharmacol Sci, 22, pp. 8030-8033. , 30536352; Freuding, M., Keinki, C., Micke, O., Buentzel, J., Huebner, J., Mistletoe in oncological treatment: a systematic review: part 1: survival and safety (2019) J Cancer Res Clin Oncol, 145, pp. 695-707. , 30673873; Freuding, M., Keinki, C., Kutschan, S., Micke, O., Buentzel, J., Huebner, J., Mistletoe in oncological treatment: a systematic review: part 2: quality of life and toxicity of cancer treatment (2019) J Cancer Res Clin Oncol, 145, pp. 927-939. , 30673872; Alizadeh-Navaei, R., Shamshirian, A., Hedayatizadeh-Omran, A., Ghadimi, R., Janbabai, G., Effect of garlic in gastric cancer prognosis: a systematic review and meta-analysis (2018) WCRJ, 5, p. e1184; Ngo, B., Van Riper, J.M., Cantley, L.C., Yun, J., Targeting cancer vulnerabilities with high-dose vitamin C (2019) Nat Rev Cancer, 19, pp. 271-282; Jafari Koulaee, A., Khenarinezhad, F., Abutalebi, M., Bagheri-Nesami, M., The effect of logotherapy on depression in cancer patients: a systematic review study (2018) WCRJ, 5, p. e1134; Alizadeh-Navaei, R., Saeedi, M., Janbabaei, G., Asgarian-Omran, H., Kelidari, H., Ahmadi-Ahangar, M., Role of vitamin D in the effectiveness of chemotherapeutic drugs on gastric cancer cell lines (2019) WCRJ, 6, p. e1259
PY - 2020
Y1 - 2020
N2 - Purpose: Complementary and Alternative Medicine (CAM) interventions are widely used by patients with chronic disorders, including cancer, and may interact with cancer treatment. Physicians are often unaware of this, probably due to poor patient-physician communication on CAM. The purpose of this study was to evaluate physicians' knowledge, attitudes and practice patterns regarding CAM in a survey conducted in Italy. Methods: A questionnaire was administered to 438 physicians (11 Italian hospitals) who predominantly treat patients with chronic disease, to collect personal and professional data and information on attitudes toward CAM and its possible role in Conventional Medicine (CM). Results: Of the 438 participants, most were specialists in oncology (18%), internal medicine (17%), surgery (15%), and radiotherapy (11%). Most worked at university (44%) or research hospitals (31%). Forty-two percent of participants believed that CAM could have an integrative role within CM. Oncologists were the physicians who were best informed on CAM (58%). Physicians working at research institutes or university hospitals had a greater knowledge of CAM than those employed at general hospitals (p < 0.0001), and those who were also involved in research activity had a greater knowledge of CAM than those who were not (p < 0.003). Length of work experience was significantly related to CAM knowledge. Moreover, 55% of participants suggest CAM interventions to their patients and 44% discuss CAM with them. The best-known interventions were acupuncture, Aloe vera and high-dose vitamin C. Conclusion: CAM use by patients with chronic disease and/or cancer has become a topical issue for the scientific community and for physicians. Knowing the reasons that prompt these patients to use CAM and guiding them in their decisions would improve treatment and outcomes and also benefit healthcare systems. Our findings contribute to a greater understanding of CAM knowledge, attitudes, and practice among Italian physicians. Further research is needed to identify the more effective CAM treatments and to work toward an integrated healthcare model. © Copyright © 2020 Berretta, Rinaldi, Taibi, Tralongo, Fulvi, Montesarchio, Madeddu, Magistri, Bimonte, Trovò, Gnagnarella, Cuomo, Cascella, Lleshi, Nasti, Facchini, Fiorica, Di Francia, Nunnari, Pellicanò, Guglielmino, Danova, Rossetti, Amore, Crispo and Facchini.
AB - Purpose: Complementary and Alternative Medicine (CAM) interventions are widely used by patients with chronic disorders, including cancer, and may interact with cancer treatment. Physicians are often unaware of this, probably due to poor patient-physician communication on CAM. The purpose of this study was to evaluate physicians' knowledge, attitudes and practice patterns regarding CAM in a survey conducted in Italy. Methods: A questionnaire was administered to 438 physicians (11 Italian hospitals) who predominantly treat patients with chronic disease, to collect personal and professional data and information on attitudes toward CAM and its possible role in Conventional Medicine (CM). Results: Of the 438 participants, most were specialists in oncology (18%), internal medicine (17%), surgery (15%), and radiotherapy (11%). Most worked at university (44%) or research hospitals (31%). Forty-two percent of participants believed that CAM could have an integrative role within CM. Oncologists were the physicians who were best informed on CAM (58%). Physicians working at research institutes or university hospitals had a greater knowledge of CAM than those employed at general hospitals (p < 0.0001), and those who were also involved in research activity had a greater knowledge of CAM than those who were not (p < 0.003). Length of work experience was significantly related to CAM knowledge. Moreover, 55% of participants suggest CAM interventions to their patients and 44% discuss CAM with them. The best-known interventions were acupuncture, Aloe vera and high-dose vitamin C. Conclusion: CAM use by patients with chronic disease and/or cancer has become a topical issue for the scientific community and for physicians. Knowing the reasons that prompt these patients to use CAM and guiding them in their decisions would improve treatment and outcomes and also benefit healthcare systems. Our findings contribute to a greater understanding of CAM knowledge, attitudes, and practice among Italian physicians. Further research is needed to identify the more effective CAM treatments and to work toward an integrated healthcare model. © Copyright © 2020 Berretta, Rinaldi, Taibi, Tralongo, Fulvi, Montesarchio, Madeddu, Magistri, Bimonte, Trovò, Gnagnarella, Cuomo, Cascella, Lleshi, Nasti, Facchini, Fiorica, Di Francia, Nunnari, Pellicanò, Guglielmino, Danova, Rossetti, Amore, Crispo and Facchini.
KW - alternative medicine
KW - attitudes
KW - cancer
KW - complementary medicine
KW - Italian survey
KW - physicians
KW - treatment
KW - ascorbic acid
KW - acupuncture
KW - adult
KW - aged
KW - allopathy
KW - Aloe vera
KW - Article
KW - cancer patient
KW - chronic disease
KW - controlled study
KW - cross-sectional study
KW - female
KW - human
KW - internal medicine
KW - Italy
KW - male
KW - medical specialist
KW - oncology
KW - perception
KW - physician attitude
KW - questionnaire
KW - radiotherapy
KW - surgery
KW - work experience
U2 - 10.3389/fonc.2020.00594
DO - 10.3389/fonc.2020.00594
M3 - Article
VL - 10
JO - Front. Oncol.
JF - Front. Oncol.
SN - 2234-943X
ER -