Abstract
Data are reported on the analytical and physicochemical characteristics of amiodarone, for use in identifying and/or assaying this antiarrhythmic agent. The drug is highly soluble in chloroform and poorly soluble in water. Its acid-base constant (pK(a) is 6.56, and its maximal lipid solubility range is from pH 3.5 to 5.5.
| Original language | English |
|---|---|
| Pages (from-to) | 829-831 |
| Number of pages | 3 |
| Journal | Journal of Pharmaceutical Sciences |
| Volume | 73 |
| Issue number | 6 |
| Publication status | Published - 1984 |
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry
- Chemistry(all)
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science