Physiological analysis of simple rapid movements in patients with cerebellar deficits

M. Hallett, A. Berardelli, J. Matheson, J. Rothwell, C. D. Marsden

Research output: Contribution to journalArticlepeer-review


Patients with cerebellar deficits made elbow flexion movements as rapidly as possible for three different angular distances. Electromyographic activity of biceps and triceps and the kinematics of the movements were analysed. Results were compared with those of normal subjects making both rapid and slow movements. In the patients, the first agonist burst of the biceps was frequently prolonged regardless of the distance or speed of the movement. The most striking kinematic abnormality was prolonged acceleration time. The pattern of acceleration time exceeding deceleration time was common in patients but uncommon in normal subjects. The best kinematic correlate of the duration of the first agonist burst was acceleration time. Altered production of appropriate acceleration may therefore be an important abnormality in cerebellar dysfunction for attempted rapid voluntary movements.

Original languageEnglish
Pages (from-to)124-133
Number of pages10
JournalJournal of Neurology, Neurosurgery and Psychiatry
Issue number2
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology


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