Objectives: To evaluate effects of meals in difficult-to-wean tracheostomised patients with chronic obstructive pulmonary diseases during spontaneous breathing or Inspiratory Pressure Support. Design: Prospective, crossover, randomised, and physiological study. Setting: Weaning centre. Patients: Sixteen COPD undergoing either decreasing levels of pressure support or increasing periods of spontaneous breathing. Measurements: Each patient underwent monitoring during a 30-min procedure, during and after meals either under pressure support or spontaneous breathing on two consecutive days. Inductance plethysmography was used to monitor respiratory rate and tidal volume. Tidal volume by a flow transducer, arterial oxygen saturation, pulse rate, end-tidal CO2 and dyspnoea by a visual analogue scale were also assessed. Results: ANOVA analysis showed a significant increase under spontaneous breathing for respiratory rate (P2 (P2, and dyspnoea; 2) inspiratory pressure support ventilation prevents dyspnoea from worsening during meals.
- Activity of daily life
- Mechanical ventilation
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine