Physiological effects of meals in difficult-to-wean tracheostomised patients with chronic obstructive pulmonary disease

Michele Vitacca, Giovanna Callegari, Maria Sarvà, Luca Bianchi, Luca Barbano, Bruno Balbi, Nicolino Ambrosino

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: To evaluate effects of meals in difficult-to-wean tracheostomised patients with chronic obstructive pulmonary diseases during spontaneous breathing or Inspiratory Pressure Support. Design: Prospective, crossover, randomised, and physiological study. Setting: Weaning centre. Patients: Sixteen COPD undergoing either decreasing levels of pressure support or increasing periods of spontaneous breathing. Measurements: Each patient underwent monitoring during a 30-min procedure, during and after meals either under pressure support or spontaneous breathing on two consecutive days. Inductance plethysmography was used to monitor respiratory rate and tidal volume. Tidal volume by a flow transducer, arterial oxygen saturation, pulse rate, end-tidal CO2 and dyspnoea by a visual analogue scale were also assessed. Results: ANOVA analysis showed a significant increase under spontaneous breathing for respiratory rate (P2 (P2, and dyspnoea; 2) inspiratory pressure support ventilation prevents dyspnoea from worsening during meals.

Original languageEnglish
Pages (from-to)236-242
Number of pages7
JournalIntensive Care Medicine
Volume31
Issue number2
DOIs
Publication statusPublished - Feb 2005

Keywords

  • Activity of daily life
  • Mechanical ventilation
  • Weaning

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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