Physiopathologie de la photosensibilité

Translated title of the contribution: Physiopathology of photosensitivity

Laura Cantonetti, Dorothee Kasteleijn Nolst Trenité, Carla Buttinelli

Research output: Contribution to journalArticlepeer-review

Abstract

Although photosensitivity is a comparatively frequent trait in children with epilepsy, and has been amply documented clinically, its physpathological bases remain unclear. Several studies have demonstrated that only selected visual stimuli, with precise physical characteristics, are likely to trigger epileptic photosensitivity. The major part played by the visual cortex in the genesis of photic sensitivity is establihed. However, paroxysmal discharges may involve extra-occipital cortical areas and follow less foreseeable brain circuits. There is probably a multifactorial genesis at the basis of such phenomenon, and the "photosensitive" phenotype is probably the expression of complex interactions between genetic and environmental factors. In this review, we will cite the main clinical and experimental findings that underly the physiopathological hypothesis outlined above.

Translated title of the contributionPhysiopathology of photosensitivity
Original languageFrench
Pages (from-to)140-144
Number of pages5
JournalEpilepsies
Volume20
Issue number3
DOIs
Publication statusPublished - Jul 2008

Keywords

  • Epileptic photosensitivity
  • Pathogenic mechanism
  • Photoparoxysmal response
  • Physiopathology
  • Visual stimulus

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

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