Pigmented purpuric dermatoses: A complete narrative review

Cristina B. Spigariolo, Serena Giacalone, Gianluca Nazzaro

Research output: Contribution to journalReview articlepeer-review

Abstract

Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed. These lesions, often asymptomatic or associated with mild pruritus, usually occur on the lower extremities and may be a diagnostic and therapeutic challenge both for general practitioners and specialists in internal medicine or flebology. Clinical presentations include many subtypes that have been described over the years, although histology is usually superimposable. Prompt recognition and patient reassurance on the benign nature of these diseases is crucial. In this comprehensive review, we focused on pathogenesis and clinical pictures.

Original languageEnglish
Article number2283
JournalJournal of Clinical Medicine
Volume10
Issue number11
DOIs
Publication statusPublished - Jun 1 2021

Keywords

  • Capillaritis
  • Dermatitis of Gougerot and Blum
  • Lichen aureus
  • Pigmented purpuric dermatosis
  • Purpura of Doucas and Kapetanakis
  • Purpura of Majocchi
  • Schamberg disease

ASJC Scopus subject areas

  • Medicine(all)

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