Pirenzepine and cimetidine in the long-term treatment of duodenal ulcer. A controlled trial

R. Farini; F. Vianello; F. Di Mario; P. Valentini; R. Cannizzaro; R. Annicchiarico; R. Naccarato

Pirenzepine and cimetidine in the long-term treatment of duodenal ulcer. A controlled trial

R. Farini, F. Vianello, F. Di Mario, P. Valentini, R. Cannizzaro, R. Annicchiarico, R. Naccarato

Centro di Riferimento Oncologico

Research output: Contribution to journal › Article › peer-review

Abstract

In this preliminary study, one year of 50 mg pirenzepine daily at night was found to be as effective and safe as 400 mg cimetidine daily at night in preventing duodenal ulcer recurrence. Eleven and 10 of the patients in each group of 15 patients, respectively, were in remission at the end of the study. No side-effects from either drug were noted. Biochemical tests showed no significant differences before or after treatment. These results suggest that pirenzepine is an effective drug in the long-term treatment of duodenal ulcer.

Original language	English
Pages (from-to)	71-76
Number of pages	6
Journal	Clinical Trials Journal
Volume	20
Issue number	2
Publication status	Published - 1983

Keywords

cimetidine
Duodenal ulcer
pirenzepine

ASJC Scopus subject areas

Pharmacology (medical)

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title = "Pirenzepine and cimetidine in the long-term treatment of duodenal ulcer. A controlled trial",

abstract = "In this preliminary study, one year of 50 mg pirenzepine daily at night was found to be as effective and safe as 400 mg cimetidine daily at night in preventing duodenal ulcer recurrence. Eleven and 10 of the patients in each group of 15 patients, respectively, were in remission at the end of the study. No side-effects from either drug were noted. Biochemical tests showed no significant differences before or after treatment. These results suggest that pirenzepine is an effective drug in the long-term treatment of duodenal ulcer.",

keywords = "cimetidine, Duodenal ulcer, pirenzepine",

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AU - Farini, R.

AU - Vianello, F.

AU - Di Mario, F.

AU - Valentini, P.

AU - Cannizzaro, R.

AU - Annicchiarico, R.

AU - Naccarato, R.

PY - 1983

Y1 - 1983

N2 - In this preliminary study, one year of 50 mg pirenzepine daily at night was found to be as effective and safe as 400 mg cimetidine daily at night in preventing duodenal ulcer recurrence. Eleven and 10 of the patients in each group of 15 patients, respectively, were in remission at the end of the study. No side-effects from either drug were noted. Biochemical tests showed no significant differences before or after treatment. These results suggest that pirenzepine is an effective drug in the long-term treatment of duodenal ulcer.

AB - In this preliminary study, one year of 50 mg pirenzepine daily at night was found to be as effective and safe as 400 mg cimetidine daily at night in preventing duodenal ulcer recurrence. Eleven and 10 of the patients in each group of 15 patients, respectively, were in remission at the end of the study. No side-effects from either drug were noted. Biochemical tests showed no significant differences before or after treatment. These results suggest that pirenzepine is an effective drug in the long-term treatment of duodenal ulcer.

KW - cimetidine

KW - Duodenal ulcer

KW - pirenzepine

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ER -

Pirenzepine and cimetidine in the long-term treatment of duodenal ulcer. A controlled trial

Abstract

Keywords

ASJC Scopus subject areas

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