Pirenzepine and cimetidine in the long-term treatment of duodenal ulcer. A controlled trial

R. Farini, F. Vianello, F. Di Mario, P. Valentini, R. Cannizzaro, R. Annicchiarico, R. Naccarato

Research output: Contribution to journalArticlepeer-review

Abstract

In this preliminary study, one year of 50 mg pirenzepine daily at night was found to be as effective and safe as 400 mg cimetidine daily at night in preventing duodenal ulcer recurrence. Eleven and 10 of the patients in each group of 15 patients, respectively, were in remission at the end of the study. No side-effects from either drug were noted. Biochemical tests showed no significant differences before or after treatment. These results suggest that pirenzepine is an effective drug in the long-term treatment of duodenal ulcer.

Original languageEnglish
Pages (from-to)71-76
Number of pages6
JournalClinical Trials Journal
Volume20
Issue number2
Publication statusPublished - 1983

Keywords

  • cimetidine
  • Duodenal ulcer
  • pirenzepine

ASJC Scopus subject areas

  • Pharmacology (medical)

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