Serum osteocalcin levels were measured in three normal subjects during a 2 h 15 min period; blood was sampled every 45 min from 7:50 a.m. to 10:05 a.m. (the time at which patients generally attend clinical centers). Serum osteocalcin levels tended to fall during this period in all three subjects studied. This study emphasizes the importance of regulating the time of blood sampling for osteocalcin measurement in clinical investigation of metabolic bone diseases.
|Number of pages||2|
|Journal||Medicina - Rivista della Enciclopedia Medica Italiana|
|Publication status||Published - 1988|
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