Pityriasis Rosea in Children: Clinical Features and Laboratory Investigations

Francesco Drago, Giulia Ciccarese, Francesco Broccolo, Emanuele Cozzani, Aurora Parodi

Research output: Contribution to journalArticlepeer-review


Pityriasis rosea (PR) is a common, self-limiting exanthematous disease associated with a systemic reactivation of human herpesvirus 6 (HHV-6) and/or HHV-7. It usually occurs in the second or third decade of life whereas it is uncommon in patients younger than 10 years. We studied the clinical features and virological parameters of 31 children with PR, comparing them with those in adults. Our findings indicate that PR presents different characteristics between children and adults, mainly consisting of time lapse between herald patch and generalized eruption, duration of the exanthem, oropharyngeal involvement and persistence of HHV-6 and HHV-7 plasma viremia. Overall, these results suggest that, following HHV-6 and/or HHV-7 systemic active infection, the pathogenetic mechanisms involved in PR may at least partly be different in children and adults.

Original languageEnglish
Pages (from-to)9-14
Number of pages6
Issue number1
Publication statusPublished - Jul 22 2015


  • Children
  • Human herpesvirus 6
  • Human herpesvirus 7
  • Pityriasis rosea

ASJC Scopus subject areas

  • Dermatology


Dive into the research topics of 'Pityriasis Rosea in Children: Clinical Features and Laboratory Investigations'. Together they form a unique fingerprint.

Cite this