Placental lesions in a case of DiGeorge sequence

E. Fulcheri, M. Gualco, F. Delfino, M. F. Pantarotto

Research output: Contribution to journalArticle

Abstract

This work describes some placental alterations found in a partial form of DiGeorge sequence, namely, hypoplasia of a cord artery with internal calcification of an extensive endoluminal thrombosis, and widespread calcification of microthrombi in the arteries of the second and third order villous branches. Hypoplasia of a cord artery is a relatively rare event, and is also associated with malformations of the gastroenteric and cardiovascular system, as sometimes described in the DiGeorge sequence. Interesting placental alterations are reported and their likely physiopathologic basis and pathogenic correlation discussed in order to give a better and more comprehensive picture of the DiGeorge sequence in which the correlated placental alterations are not sufficiently known.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalFetal Diagnosis and Therapy
Volume21
Issue number1
DOIs
Publication statusPublished - Dec 2005

Keywords

  • Artery hypoplasia
  • DiGeorge sequence
  • Placenta
  • Vessel calcifications

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Pediatrics, Perinatology, and Child Health

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