Abstract
Objective: To determine whether the net release of β-endorphin during exercise, similar to that of norepinephrine, is related to functional disability in patients with congestive heart failure. Background: Plasma β- endorphin and norepinephrine levels are elevated at rest in patients with heart failure, reflecting a functional disability. The net release of β- endorphin during exercise in patients with heart failure is unknown. Methods: We measured plasma β-endorphin and norepinephrine levels (respectively: radioimmune and radioenzymatic assay) at rest and during graded exercise testing in 28 patients with congestive heart failure (Weber's class A, 10; B, 9; and C, 9) and in 9 normal subjects. Results: At rest, plasma β-endorphin levels were higher in patients in classes B and C than in normal subjects (p
| Original language | English |
|---|---|
| Pages (from-to) | 19-22 |
| Number of pages | 4 |
| Journal | Chest |
| Volume | 111 |
| Issue number | 1 |
| Publication status | Published - 1997 |
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine