Abstract
Plasma and urinary GH responses following acute physical exercise were evaluated in 19 short-statured children (12 males, 7 females, median age: 11.4 yr, age range: 6.1-14.5 yr, Tanner stage I-III, height ≤3rd centile for age; 7 with familial short stature, FSS; 8 with constitutional growth delay, CGD; 4 with GH deficiency, GHD) and 7 normally growing, age- and sex-matched control children (4 males, 3 females, median age 11.0 yr, range: 7.2-13.1 yr, Tanner stage I-III). All patients and controls underwent a standardized exercise protocol (consisting of jogging up and down a corridor for 15 min, strongly encouraged to produce the maximum possible effort, corresponding to 70-80% of the maximal heart rate) after an overnight fasting. Samples for plasma GH determinations were drawn at 0 time (baseline), at 20 min (5 min after the end of exercise) and at 35 min (after 20 min of rest); urine samples were collected before (0 time) and at 40, 80 and 120 min after exercise. The distance covered by children with GHD during the test was significantly lower (p
| Original language | English |
|---|---|
| Pages (from-to) | 515-521 |
| Number of pages | 7 |
| Journal | Journal of Endocrinological Investigation |
| Volume | 24 |
| Issue number | 7 |
| Publication status | Published - 2001 |
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Keywords
- Children
- GH
- Physical exercise
- Short stature
ASJC Scopus subject areas
- Endocrinology
Cite this
Plasma and urinary GH following a standardized exercise protocol to assess GH production in short children. / Sartorio, A.; Palmieri, E.; Vangeli, V.; Conte, G.; Narici, M.; Faglia, G.
In: Journal of Endocrinological Investigation, Vol. 24, No. 7, 2001, p. 515-521.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Plasma and urinary GH following a standardized exercise protocol to assess GH production in short children
AU - Sartorio, A.
AU - Palmieri, E.
AU - Vangeli, V.
AU - Conte, G.
AU - Narici, M.
AU - Faglia, G.
PY - 2001
Y1 - 2001
N2 - Plasma and urinary GH responses following acute physical exercise were evaluated in 19 short-statured children (12 males, 7 females, median age: 11.4 yr, age range: 6.1-14.5 yr, Tanner stage I-III, height ≤3rd centile for age; 7 with familial short stature, FSS; 8 with constitutional growth delay, CGD; 4 with GH deficiency, GHD) and 7 normally growing, age- and sex-matched control children (4 males, 3 females, median age 11.0 yr, range: 7.2-13.1 yr, Tanner stage I-III). All patients and controls underwent a standardized exercise protocol (consisting of jogging up and down a corridor for 15 min, strongly encouraged to produce the maximum possible effort, corresponding to 70-80% of the maximal heart rate) after an overnight fasting. Samples for plasma GH determinations were drawn at 0 time (baseline), at 20 min (5 min after the end of exercise) and at 35 min (after 20 min of rest); urine samples were collected before (0 time) and at 40, 80 and 120 min after exercise. The distance covered by children with GHD during the test was significantly lower (p
AB - Plasma and urinary GH responses following acute physical exercise were evaluated in 19 short-statured children (12 males, 7 females, median age: 11.4 yr, age range: 6.1-14.5 yr, Tanner stage I-III, height ≤3rd centile for age; 7 with familial short stature, FSS; 8 with constitutional growth delay, CGD; 4 with GH deficiency, GHD) and 7 normally growing, age- and sex-matched control children (4 males, 3 females, median age 11.0 yr, range: 7.2-13.1 yr, Tanner stage I-III). All patients and controls underwent a standardized exercise protocol (consisting of jogging up and down a corridor for 15 min, strongly encouraged to produce the maximum possible effort, corresponding to 70-80% of the maximal heart rate) after an overnight fasting. Samples for plasma GH determinations were drawn at 0 time (baseline), at 20 min (5 min after the end of exercise) and at 35 min (after 20 min of rest); urine samples were collected before (0 time) and at 40, 80 and 120 min after exercise. The distance covered by children with GHD during the test was significantly lower (p
KW - Children
KW - GH
KW - Physical exercise
KW - Short stature
UR - http://www.scopus.com/inward/record.url?scp=0034920136&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034920136&partnerID=8YFLogxK
M3 - Article
C2 - 11508786
AN - SCOPUS:0034920136
VL - 24
SP - 515
EP - 521
JO - Journal of Endocrinological Investigation
JF - Journal of Endocrinological Investigation
SN - 0391-4097
IS - 7
ER -