Plasma beta - thromboglobulin concentration at rest and after physical exercise in complicated and uncomplicated diabetes mellitus

A. M. Vicari, A. Margonato, P. Petrelli, G. G. Vicedomini, G. Pozza

Research output: Contribution to journalArticlepeer-review

Abstract

Plasma beta-thromboglobulin concentration was measured in ten uncomplicated insulin-dependent diabetic subjects, in ten insulin-dependent patients with retinopathy and in ten age- and sex-matched healthy controls, both at rest and after cycloergometric exercise to exhaustion. Resting plasma beta-thromboglobulin was similar in the two patient groups and significantly higher than the control group. After exercising, plasma beta-thromboglobulin rose significantly only in the control group. Platelet hyperactivity is therefore present even in uncomplicated diabetes mellitus and is not influenced by the presence of complications. A chronic overstimulation of platelets could be responsible for the high basal plasma beta-thromboglobulin concentration in diabetes mellitus and for its abnormal behaviour after physical exercise.

Original languageEnglish
Pages (from-to)235-238
Number of pages4
JournalDiabete et Metabolisme
Volume10
Issue number4
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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