Plasma carotenoid and malondialdehyde levels in ischemic stroke patients: Relationship to early outcome

M. Cristina Polidori, Antonio Cherubini, Wilhelm Stahl, Umberto Senin, Helmut Sies, Patrizia Mecocci

Research output: Contribution to journalArticlepeer-review

Abstract

An association between ischemic stroke and increased oxidative stress has been suggested from animal studies. However, there is a lack of evidence with respect to this association in humans. Here, the time course of plasma levels of six carotenoids, which are lipophilic micronutrients with antioxidant properties, as well as of malondialdehyde (MDA), a marker of lipid peroxidation, was followed in ischemic stroke patients. Plasma levels of lutein, zeaxanthin, β-cryptoxanthin, lycopene, α- and β-carotene, as well as MDA were measured by high-performance liquid chromatography in 28 subjects (19 men and nine women aged 76.9 ± 8.7 years) with an acute ischemic stroke of recent onset (

Original languageEnglish
Pages (from-to)265-268
Number of pages4
JournalFree Radical Research
Volume36
Issue number3
DOIs
Publication statusPublished - Mar 1 2002

Keywords

  • Antioxidants
  • Carotenoids
  • Outcome
  • Oxidative stress
  • Stroke

ASJC Scopus subject areas

  • Biochemistry

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