TY - JOUR
T1 - Plasma carotenoid and malondialdehyde levels in ischemic stroke patients
T2 - Relationship to early outcome
AU - Polidori, M. Cristina
AU - Cherubini, Antonio
AU - Stahl, Wilhelm
AU - Senin, Umberto
AU - Sies, Helmut
AU - Mecocci, Patrizia
PY - 2002/3/1
Y1 - 2002/3/1
N2 - An association between ischemic stroke and increased oxidative stress has been suggested from animal studies. However, there is a lack of evidence with respect to this association in humans. Here, the time course of plasma levels of six carotenoids, which are lipophilic micronutrients with antioxidant properties, as well as of malondialdehyde (MDA), a marker of lipid peroxidation, was followed in ischemic stroke patients. Plasma levels of lutein, zeaxanthin, β-cryptoxanthin, lycopene, α- and β-carotene, as well as MDA were measured by high-performance liquid chromatography in 28 subjects (19 men and nine women aged 76.9 ± 8.7 years) with an acute ischemic stroke of recent onset (
AB - An association between ischemic stroke and increased oxidative stress has been suggested from animal studies. However, there is a lack of evidence with respect to this association in humans. Here, the time course of plasma levels of six carotenoids, which are lipophilic micronutrients with antioxidant properties, as well as of malondialdehyde (MDA), a marker of lipid peroxidation, was followed in ischemic stroke patients. Plasma levels of lutein, zeaxanthin, β-cryptoxanthin, lycopene, α- and β-carotene, as well as MDA were measured by high-performance liquid chromatography in 28 subjects (19 men and nine women aged 76.9 ± 8.7 years) with an acute ischemic stroke of recent onset (
KW - Antioxidants
KW - Carotenoids
KW - Outcome
KW - Oxidative stress
KW - Stroke
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U2 - 10.1080/10715760290019273
DO - 10.1080/10715760290019273
M3 - Article
C2 - 12071344
AN - SCOPUS:0036521850
VL - 36
SP - 265
EP - 268
JO - Free Radical Research
JF - Free Radical Research
SN - 1071-5762
IS - 3
ER -