Plasma Exchange Ineffective in Amyotrophic Lateral Sclerosis

Vincenzo Silani, Guglielmo Scarlato, Giorgio Valli, Maurizio Marconi

Research output: Contribution to journalArticlepeer-review


The effectiveness of plasma exchange in amyotrophic lateral sclerosis (ALS) was tested in four patients. Electromyography (EMG) and clinical examinations were carried out before, during, and after the treatment. The EMG data showed a progressive unaffected motor neuronal decay. Clinically the course of the disease was not dissimilar to that usually encountered, although a momentary improvement was observed in two patients after the first procedure. Plasma exchange appears to be of no value in treating ALS.

Original languageEnglish
Pages (from-to)511-513
Number of pages3
JournalArchives of Neurology
Issue number8
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology
  • Neuroscience(all)


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