Plasma exchange therapy in rapidly progressive renal failure due to multiple myeloma

S. Pasquali, L. Cagnoli, C. Rovinetti, A. Rigotti, P. Zucchelli

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Nineteen patients with severe renal failure due to multiple myeloma and with Bence Jones proteinuria > 1 gm/day were randomly assigned to group I or group II. Corticosteroids and cytotoxic drugs were given to all cases. The 9 patients of group I were also treated by peritoneal dialysis and the 10 patients of group II by plasma exchange and hemodialysis. Only 1 patient of group I, who was not oliguric at the onset, showed partial recovery from renal failure after 3 months of therapy, while 9 patients of group II (3 of whom were oliguric) had a significant decrease in Bence Jones proteinuria and rapid improvement of the renal failure. In our experience, plasma exchange is more effective than peritoneal dialysis for reducing Bence Jones proteinuria and recovering from renal failure, even when there is oliguria.

Original languageEnglish
Pages (from-to)27-30
Number of pages4
JournalInternational Journal of Artificial Organs
Volume8
Issue numberSUPPL. 2
Publication statusPublished - 1985

Fingerprint

Plasma Exchange
Dialysis
Multiple Myeloma
Renal Insufficiency
Plasmas
Proteinuria
Peritoneal Dialysis
Ion exchange
Adrenal Cortex Hormones
Recovery
Oliguria
Therapeutics
Pharmaceutical Preparations
Renal Dialysis

ASJC Scopus subject areas

  • Biophysics

Cite this

Pasquali, S., Cagnoli, L., Rovinetti, C., Rigotti, A., & Zucchelli, P. (1985). Plasma exchange therapy in rapidly progressive renal failure due to multiple myeloma. International Journal of Artificial Organs, 8(SUPPL. 2), 27-30.

Plasma exchange therapy in rapidly progressive renal failure due to multiple myeloma. / Pasquali, S.; Cagnoli, L.; Rovinetti, C.; Rigotti, A.; Zucchelli, P.

In: International Journal of Artificial Organs, Vol. 8, No. SUPPL. 2, 1985, p. 27-30.

Research output: Contribution to journalArticle

Pasquali, S, Cagnoli, L, Rovinetti, C, Rigotti, A & Zucchelli, P 1985, 'Plasma exchange therapy in rapidly progressive renal failure due to multiple myeloma', International Journal of Artificial Organs, vol. 8, no. SUPPL. 2, pp. 27-30.
Pasquali S, Cagnoli L, Rovinetti C, Rigotti A, Zucchelli P. Plasma exchange therapy in rapidly progressive renal failure due to multiple myeloma. International Journal of Artificial Organs. 1985;8(SUPPL. 2):27-30.
Pasquali, S. ; Cagnoli, L. ; Rovinetti, C. ; Rigotti, A. ; Zucchelli, P. / Plasma exchange therapy in rapidly progressive renal failure due to multiple myeloma. In: International Journal of Artificial Organs. 1985 ; Vol. 8, No. SUPPL. 2. pp. 27-30.
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