Plasma fibronectin, von Willebrand factor antigen, and blood rheology. Association with diabetic microvascular disease

Sebastiano Bruno Solerte, Franco Piovella, Cristina Viola, Giampiero Carnevale Schianca, Gabriella Gamba, Marisa Fioravanti, Ettore Ferrari

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Plasma fibronectin might play a role in the pathogeneis and progression of diabetic microvascular disease. To test this hypothesis we measured plasma fibronectin, von Willebrand factor antigen, fibrinogen, erythrocyte filtrability, whole-blood viscosity, proteinuria and albuminuria in 25 control subjects and 29 diabetic patients with and without microvascular complications. Plasma fibronectin was significantly higher in the diabetic patients, especially in those with retinopathy and nephropathy. A significant correlation between fibronectin and von Willebrand factor antigen was found in both patients with and without microangiopathy (p

Original languageEnglish
Pages (from-to)239-246
Number of pages8
JournalActa Diabetologica Latina
Volume22
Issue number3
DOIs
Publication statusPublished - Jul 1985

Fingerprint

Rheology
von Willebrand Factor
Fibronectins
Blood Viscosity
Albuminuria
Proteinuria
Fibrinogen
Erythrocytes
Von Willebrand antigen

Keywords

  • Blood viscosity
  • Diabetes mellitus
  • Erythrocyte filtrability
  • Fibronectin
  • Nephropathy
  • Retinopathy
  • von Willebrand factor

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Plasma fibronectin, von Willebrand factor antigen, and blood rheology. Association with diabetic microvascular disease. / Solerte, Sebastiano Bruno; Piovella, Franco; Viola, Cristina; Schianca, Giampiero Carnevale; Gamba, Gabriella; Fioravanti, Marisa; Ferrari, Ettore.

In: Acta Diabetologica Latina, Vol. 22, No. 3, 07.1985, p. 239-246.

Research output: Contribution to journalArticle

Solerte, Sebastiano Bruno ; Piovella, Franco ; Viola, Cristina ; Schianca, Giampiero Carnevale ; Gamba, Gabriella ; Fioravanti, Marisa ; Ferrari, Ettore. / Plasma fibronectin, von Willebrand factor antigen, and blood rheology. Association with diabetic microvascular disease. In: Acta Diabetologica Latina. 1985 ; Vol. 22, No. 3. pp. 239-246.
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