Plasma interleukin-1β and tumor necrosis factor concentrations in obsessive-compulsive disorders

Francesca Brambilla, Giampaolo Perna, Laura Bellodi, Cinzia Arancio, Angelo Bertani, Giulia Perini, Christian Carraro, Franco Gava

Research output: Contribution to journalArticle

Abstract

Plasma interleukin-1β (Il-1β) and tumor necrosis factor-α (TNF-α) concentrations were measured twice, at a 48-hour interval, in 27 drug-free obsessive-compulsive patients (12 women and 15 men) and in 27 sex-age-matched healthy controls. Il-1β and TNF-α concentrations were significantly lower in patients than in controls, whereas there were no differences in either group between men and women, between the samples of the two days, or, in the patients, between those who had and those who had not been previously treated with psychopharmacologic drugs.

Original languageEnglish
Pages (from-to)976-981
Number of pages6
JournalBiological Psychiatry
Volume42
Issue number11
DOIs
Publication statusPublished - Dec 1 1997

Keywords

  • interleukin-1β
  • obsessive-compulsive disorders
  • tumor necrosis factor-α

ASJC Scopus subject areas

  • Biological Psychiatry

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    Brambilla, F., Perna, G., Bellodi, L., Arancio, C., Bertani, A., Perini, G., Carraro, C., & Gava, F. (1997). Plasma interleukin-1β and tumor necrosis factor concentrations in obsessive-compulsive disorders. Biological Psychiatry, 42(11), 976-981. https://doi.org/10.1016/S0006-3223(96)00495-7