Plasma kinetic of ingested essential amino acids in healthy elderly people

Anna Maria Condino, Roberto Aquilani, Evasio Pasini, Paolo Iadarola, Simona Viglio, Manuela Verri, Luca D'Agostino, Federica Boschi

Research output: Contribution to journalArticlepeer-review


The purpose of this study was to investigate whether the documented difficulties of physiological amounts of essential amino acids (EAAs) (7 g) to induce protein synthesis could be reflected in a simple method adaptable to a clinical setting. Sixteen healthy individuals, nine elderly (75.3 ± 3.5 years), and seven young (28 ± 2.5 years) were enrolled in the study. Five minutes before EAA ingestion (baseline) and 20, 40, 60, 90, 120, 180 min after EAA ingestion, venous blood samples were taken from the ante-cubital vein to determine the concentrations of EAAs (μmol/L). The results show that plasma EAA increases were significantly higher in old than in young persons at the considered time points (from p

Original languageEnglish
Pages (from-to)711-714
Number of pages4
JournalAging clinical and experimental research
Issue number6
Publication statusPublished - Dec 2013


  • EAAs plasma profile
  • Elderly
  • Essential amino acids (EAAs)
  • Skeletal muscle

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology


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