Abstract
This investigation compares the levels of plasma kinetics of plasma essential amino acids (EAAs) after ingestion as free-form EAAs (FEAAs) or EAAs as components of dietary protein (DPEAAs), in eighteen healthy individuals, nine elderly (85 ± 6.7 years; 4 male) and nine young (28.7 ± 7 years; 3 males). For two consecutive days, each subject ingested EAAs in the form of (FEAAs) or (DPEAAs) in a random alternate pattern. Five minutes before EAA ingestion (baseline) and 30, 60, 90, 150 and 270 min after, venous blood samples were taken to determine the concentrations of EAAS (micromol/L). In both groups, ingested FEAAs compared to DPEAAs led to faster increase in plasma EAA levels at 30–150 min (p <0.0001). Moreover, the increased plasma EAAs disappeared faster after FEAA compared to DPEAA. These results may be important in those subjects who have high requirement both for EAAs substrates and anabolic efficiency.
| Original language | English |
|---|---|
| Pages (from-to) | 1-5 |
| Number of pages | 5 |
| Journal | Aging clinical and experimental research |
| DOIs | |
| Publication status | Published - 2016 |
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Keywords
- Elderly
- Essential amino acids
- Skeletal muscle
ASJC Scopus subject areas
- Ageing
- Geriatrics and Gerontology
Cite this
Plasma kinetics of essential amino acids following their ingestion as free formula or as dietary protein components. / Rondanelli, Mariangela; Aquilani, Roberto; Verri, Manuela; Boschi, Federica; Pasini, Evasio; Perna, Simone; Faliva, Anna; Condino, Anna Maria.
In: Aging clinical and experimental research, 2016, p. 1-5.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Plasma kinetics of essential amino acids following their ingestion as free formula or as dietary protein components
AU - Rondanelli, Mariangela
AU - Aquilani, Roberto
AU - Verri, Manuela
AU - Boschi, Federica
AU - Pasini, Evasio
AU - Perna, Simone
AU - Faliva, Anna
AU - Condino, Anna Maria
PY - 2016
Y1 - 2016
N2 - This investigation compares the levels of plasma kinetics of plasma essential amino acids (EAAs) after ingestion as free-form EAAs (FEAAs) or EAAs as components of dietary protein (DPEAAs), in eighteen healthy individuals, nine elderly (85 ± 6.7 years; 4 male) and nine young (28.7 ± 7 years; 3 males). For two consecutive days, each subject ingested EAAs in the form of (FEAAs) or (DPEAAs) in a random alternate pattern. Five minutes before EAA ingestion (baseline) and 30, 60, 90, 150 and 270 min after, venous blood samples were taken to determine the concentrations of EAAS (micromol/L). In both groups, ingested FEAAs compared to DPEAAs led to faster increase in plasma EAA levels at 30–150 min (p <0.0001). Moreover, the increased plasma EAAs disappeared faster after FEAA compared to DPEAA. These results may be important in those subjects who have high requirement both for EAAs substrates and anabolic efficiency.
AB - This investigation compares the levels of plasma kinetics of plasma essential amino acids (EAAs) after ingestion as free-form EAAs (FEAAs) or EAAs as components of dietary protein (DPEAAs), in eighteen healthy individuals, nine elderly (85 ± 6.7 years; 4 male) and nine young (28.7 ± 7 years; 3 males). For two consecutive days, each subject ingested EAAs in the form of (FEAAs) or (DPEAAs) in a random alternate pattern. Five minutes before EAA ingestion (baseline) and 30, 60, 90, 150 and 270 min after, venous blood samples were taken to determine the concentrations of EAAS (micromol/L). In both groups, ingested FEAAs compared to DPEAAs led to faster increase in plasma EAA levels at 30–150 min (p <0.0001). Moreover, the increased plasma EAAs disappeared faster after FEAA compared to DPEAA. These results may be important in those subjects who have high requirement both for EAAs substrates and anabolic efficiency.
KW - Elderly
KW - Essential amino acids
KW - Skeletal muscle
UR - http://www.scopus.com/inward/record.url?scp=84978128626&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84978128626&partnerID=8YFLogxK
U2 - 10.1007/s40520-016-0605-7
DO - 10.1007/s40520-016-0605-7
M3 - Article
AN - SCOPUS:84978128626
SP - 1
EP - 5
JO - Aging clinical and experimental research
JF - Aging clinical and experimental research
SN - 1594-0667
ER -