Plasma kinetics of essential amino acids following their ingestion as free formula or as dietary protein components

Mariangela Rondanelli, Roberto Aquilani, Manuela Verri, Federica Boschi, Evasio Pasini, Simone Perna, Anna Faliva, Anna Maria Condino

Research output: Contribution to journalArticle

Abstract

This investigation compares the levels of plasma kinetics of plasma essential amino acids (EAAs) after ingestion as free-form EAAs (FEAAs) or EAAs as components of dietary protein (DPEAAs), in eighteen healthy individuals, nine elderly (85 ± 6.7 years; 4 male) and nine young (28.7 ± 7 years; 3 males). For two consecutive days, each subject ingested EAAs in the form of (FEAAs) or (DPEAAs) in a random alternate pattern. Five minutes before EAA ingestion (baseline) and 30, 60, 90, 150 and 270 min after, venous blood samples were taken to determine the concentrations of EAAS (micromol/L). In both groups, ingested FEAAs compared to DPEAAs led to faster increase in plasma EAA levels at 30–150 min (p <0.0001). Moreover, the increased plasma EAAs disappeared faster after FEAA compared to DPEAA. These results may be important in those subjects who have high requirement both for EAAs substrates and anabolic efficiency.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalAging clinical and experimental research
DOIs
Publication statusPublished - 2016

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Essential Amino Acids
Dietary Proteins
Eating

Keywords

  • Elderly
  • Essential amino acids
  • Skeletal muscle

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

Cite this

Plasma kinetics of essential amino acids following their ingestion as free formula or as dietary protein components. / Rondanelli, Mariangela; Aquilani, Roberto; Verri, Manuela; Boschi, Federica; Pasini, Evasio; Perna, Simone; Faliva, Anna; Condino, Anna Maria.

In: Aging clinical and experimental research, 2016, p. 1-5.

Research output: Contribution to journalArticle

Rondanelli, Mariangela ; Aquilani, Roberto ; Verri, Manuela ; Boschi, Federica ; Pasini, Evasio ; Perna, Simone ; Faliva, Anna ; Condino, Anna Maria. / Plasma kinetics of essential amino acids following their ingestion as free formula or as dietary protein components. In: Aging clinical and experimental research. 2016 ; pp. 1-5.
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