Abstract
INTRODUCTION: Lactoferrin (Lf) is one of the major proteins of all exocrine secretions with a role in the antinfective process. Our aim was to evaluate how plasma Fl levels may change in response to infection in newborn preterm infants. METHODS: A total of 15 (8 females, 7 males) newborn preterm infants with a postnatal age >72 h of life, underwent to blood culture and others markers of infection, for suspected sepsis, were enrolled in the study. RESULTS: We found that Lf serum concentration was significantly lowest in four neonates (26.7%) with confirmed sepsis than in 11 (73.3%) with clinical sepsis. The AUC was 0.90 (95%CI: 0.63-0.99). The optimal cutoff for Lf was
Original language | English |
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Pages (from-to) | 2890-2893 |
Number of pages | 4 |
Journal | Journal of Maternal-Fetal and Neonatal Medicine |
Volume | 30 |
Issue number | 23 |
DOIs | |
Publication status | Published - Dec 1 2017 |
Keywords
- Lactoferrin
- immune system
- newborn preterm infants
- sepsis