Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 2890-2893 |
| Number of pages | 4 |
| Journal | Journal of Maternal-Fetal and Neonatal Medicine |
| Volume | 30 |
| Issue number | 23 |
| DOIs | |
| Publication status | Published - Dec 1 2017 |
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Keywords
- Lactoferrin
- immune system
- newborn preterm infants
- sepsis
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Plasma lactoferrin levels in newborn preterm infants with sepsis. / Decembrino, L.; DeAmici, M.; Silvestri, A. De; Manzoni, P.; Paolillo, P.; Stronati, M.
In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 30, No. 23, 01.12.2017, p. 2890-2893.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Plasma lactoferrin levels in newborn preterm infants with sepsis
AU - Decembrino, L.
AU - DeAmici, M.
AU - Silvestri, A. De
AU - Manzoni, P.
AU - Paolillo, P.
AU - Stronati, M.
N1 - LR: 20170925; JID: 101136916; OTO: NOTNLM; 2016/12/21 06:00 [pubmed]; 2016/12/21 06:00 [medline]; 2016/12/21 06:00 [entrez]; ppublish
PY - 2017/12/1
Y1 - 2017/12/1
N2 - INTRODUCTION: Lactoferrin (Lf) is one of the major proteins of all exocrine secretions with a role in the antinfective process. Our aim was to evaluate how plasma Fl levels may change in response to infection in newborn preterm infants. METHODS: A total of 15 (8 females, 7 males) newborn preterm infants with a postnatal age >72 h of life, underwent to blood culture and others markers of infection, for suspected sepsis, were enrolled in the study. RESULTS: We found that Lf serum concentration was significantly lowest in four neonates (26.7%) with confirmed sepsis than in 11 (73.3%) with clinical sepsis. The AUC was 0.90 (95%CI: 0.63-0.99). The optimal cutoff for Lf was
AB - INTRODUCTION: Lactoferrin (Lf) is one of the major proteins of all exocrine secretions with a role in the antinfective process. Our aim was to evaluate how plasma Fl levels may change in response to infection in newborn preterm infants. METHODS: A total of 15 (8 females, 7 males) newborn preterm infants with a postnatal age >72 h of life, underwent to blood culture and others markers of infection, for suspected sepsis, were enrolled in the study. RESULTS: We found that Lf serum concentration was significantly lowest in four neonates (26.7%) with confirmed sepsis than in 11 (73.3%) with clinical sepsis. The AUC was 0.90 (95%CI: 0.63-0.99). The optimal cutoff for Lf was
KW - Lactoferrin
KW - immune system
KW - newborn preterm infants
KW - sepsis
U2 - 10.1080/14767058.2016.1266479 [doi]
DO - 10.1080/14767058.2016.1266479 [doi]
M3 - Article
VL - 30
SP - 2890
EP - 2893
JO - Journal of Maternal-Fetal and Neonatal Medicine
JF - Journal of Maternal-Fetal and Neonatal Medicine
SN - 1476-7058
IS - 23
ER -