Plasma levels of dimethylarginines in preterm very low birth weight neonates: Its relation with perinatal factors and short-term outcome

Rob M. Moonen, Maurice J. Huizing, Giacomo Cavallaro, Gema E. González-Luis, Pilar Bas-Suárez, Jaap A. Bakker, Eduardo Villamor

Research output: Contribution to journalArticlepeer-review

Abstract

Endogenously produced inhibitors of nitric oxide (NO) synthase, in particular asymmetric dimethylarginine (ADMA), are currently considered of importance in various disease states characterized by reduced NO availability. We investigated the association between plasma levels of ADMA, symmetric dimethylarginine (SDMA), L-arginine, and citrulline and perinatal factors and outcome in 130 preterm (gestational age ≤30 weeks) very low birth weight (VLBW,

Original languageEnglish
Pages (from-to)19-39
Number of pages21
JournalInternational Journal of Molecular Sciences
Volume16
Issue number1
DOIs
Publication statusPublished - Dec 23 2015

Keywords

  • Arginine
  • Chrorioamnionitis
  • Dimethylarginine
  • Nitric oxide
  • Preeclampsia
  • Preterm infants
  • Respiratory distress

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Spectroscopy
  • Inorganic Chemistry
  • Catalysis
  • Molecular Biology
  • Computer Science Applications

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