Plasma levels of tumor necrosis factor-alpha in patients with panic disorder: Effect of alprazolam therapy

Francesca Brambilla, Laura Bellodi, Giampaolo Perna

Research output: Contribution to journalArticlepeer-review

Abstract

Plasma concentrations of tumor necrosis factor-α (TNF-α) were measured in 10 outpatients with panic disorder, twice (at a 48-h interval) before and twice on days 30-32 of treatment with alprazolam (2-2.5 mg/day), and twice in 10 age- and sex-matched healthy controls. TNF-α concentrations did not differ in patients and control subjects, either before therapy or at days 30-32 of therapy. In five patients before therapy, and in three of them after therapy, TNF-α values were higher than the maximal concentrations of the cytokine in controls. Copyright (C) 1999 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)21-27
Number of pages7
JournalPsychiatry Research
Volume89
Issue number1
DOIs
Publication statusPublished - Dec 13 1999

Keywords

  • Agoraphobla
  • Alprazolam
  • Anxiety
  • Cytokines
  • Immunology

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

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