Plasma prolactin levels in the inferior petrosal sinuses in various pituitary disorders during perihypophyseal phlebography

Gaetano Lombardi, Bartolomeo Merola, Paolo Miletto, Annamaria Colao, Giovanni de Chiara, Vittorio Iaccarino, Renato Spaziante, Gianfranco Di Renzo, Maurizio Taglialatela, Lucio Annunziato

Research output: Contribution to journalArticle

Abstract

The use of intercavernous sinus phlebography for the diagnosis and neurosurgical treatment of pituitary adenomas has enabled the collection of selective venous samplings of the inferior petrosal sinuses (I PSs), where prolactin (PRL) levels can be measured before the hormone becomes excessively diluted in the systemic circulation. In the present study, plasma PRL levels were studied in the right and/or left I PS and, simultaneously, in the peripheral circulation of: (l)normoprolactine-mic patients affected with various pituitary disorders which required phlebographic procedures; (2) hyperprolactinemic patients with negative radiological and computed tomographic (CT) signs of pituitary adenomas and (3 (adenomatous hyperprolactinemic patients. In the 17 normoprolactinemic patients, the plasma PRL concentration in the I PSs was significantly higher (3.5 times; p

Original languageEnglish
Pages (from-to)333-338
Number of pages6
JournalNeuroendocrinology
Volume46
Issue number4
DOIs
Publication statusPublished - 1987

Keywords

  • Inferior petrosal sinuses
  • Phlebography
  • Pituitary disorders
  • Prolactin

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Cellular and Molecular Neuroscience
  • Endocrine and Autonomic Systems
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Plasma prolactin levels in the inferior petrosal sinuses in various pituitary disorders during perihypophyseal phlebography'. Together they form a unique fingerprint.

  • Cite this

    Lombardi, G., Merola, B., Miletto, P., Colao, A., de Chiara, G., Iaccarino, V., Spaziante, R., Di Renzo, G., Taglialatela, M., & Annunziato, L. (1987). Plasma prolactin levels in the inferior petrosal sinuses in various pituitary disorders during perihypophyseal phlebography. Neuroendocrinology, 46(4), 333-338. https://doi.org/10.1159/000124841