Plasma renin activity in primary and secondary depression

A. C. Altamura; A. Morganti; E. Smeraldi; A. Zanchetti

doi:10.1007/BF00341613

Plasma renin activity in primary and secondary depression

A. C. Altamura, A. Morganti, E. Smeraldi, A. Zanchetti

Research output: Contribution to journal › Article › peer-review

Abstract

Plasma renin activity (PRA), both in supine and standing position, was investigated in primary and secondary depressed patients. After orthostatic stimulation (standing position) primary depressed patients showed PRA values significantly lower than did those with secondary depression. The authors stress the importance of the peripheral sympathetic system in the control of renin release and discuss the data obtained in the light of some evidence in the literature indicating a possible impairment of transmitter turnover in central and peripheral noradrenergic synapses in the pathogenesis of primary depression.

Original language	English
Pages (from-to)	313-318
Number of pages	6
Journal	Archiv für Psychiatrie und Nervenkrankheiten Vereinigt mit Zeitschrift für die Gesamte Neurologie und Psychiatrie
Volume	224
Issue number	4
DOIs	https://doi.org/10.1007/BF00341613
Publication status	Published - Dec 1977

Keywords

Noradrenergic system
Plasma renin activity
Primary and secondary depression

ASJC Scopus subject areas

Neuropsychology and Physiological Psychology
Psychiatry and Mental health
Clinical Neurology
Medicine(all)

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10.1007/BF00341613

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Plasma renin activity in primary and secondary depression

Abstract

Keywords

ASJC Scopus subject areas

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