Abstract
Treatment of rats for 10 estral cycles with an estrogen-progestogen combination giving 100% infertility triggered a vascular response characterized by increased prostacyclin activity in arterial walls and increased systolic blood pressure. In contrast, plasma fibrinolytic activity and physiological coagulation inhibitors as well as vascular fibrinolytic activity were not changed by this treatment. The same rats tended to have shorter occlusion times of an aortic prosthesis, and could represent a useful model to study the blood-vessel-wall interplay during oral contraceptive treatment.
| Original language | English |
|---|---|
| Pages (from-to) | 249-257 |
| Number of pages | 9 |
| Journal | Contraception |
| Volume | 22 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1980 |
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ASJC Scopus subject areas
- Medicine(all)
- Obstetrics and Gynaecology
Cite this
Plasmatic and vascular factors of the hemostatic system in rats receiving an estrogen-progestogen combination. / Roncaglioni, Maria Carla; di Minno, Giovanni; Pangrazzi, Jerta; Reyers, Ine; Mussoni, Luciana; de Gaetano, Giovanni; Benedetta Donati, Maria.
In: Contraception, Vol. 22, No. 3, 1980, p. 249-257.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Plasmatic and vascular factors of the hemostatic system in rats receiving an estrogen-progestogen combination
AU - Roncaglioni, Maria Carla
AU - di Minno, Giovanni
AU - Pangrazzi, Jerta
AU - Reyers, Ine
AU - Mussoni, Luciana
AU - de Gaetano, Giovanni
AU - Benedetta Donati, Maria
PY - 1980
Y1 - 1980
N2 - Treatment of rats for 10 estral cycles with an estrogen-progestogen combination giving 100% infertility triggered a vascular response characterized by increased prostacyclin activity in arterial walls and increased systolic blood pressure. In contrast, plasma fibrinolytic activity and physiological coagulation inhibitors as well as vascular fibrinolytic activity were not changed by this treatment. The same rats tended to have shorter occlusion times of an aortic prosthesis, and could represent a useful model to study the blood-vessel-wall interplay during oral contraceptive treatment.
AB - Treatment of rats for 10 estral cycles with an estrogen-progestogen combination giving 100% infertility triggered a vascular response characterized by increased prostacyclin activity in arterial walls and increased systolic blood pressure. In contrast, plasma fibrinolytic activity and physiological coagulation inhibitors as well as vascular fibrinolytic activity were not changed by this treatment. The same rats tended to have shorter occlusion times of an aortic prosthesis, and could represent a useful model to study the blood-vessel-wall interplay during oral contraceptive treatment.
UR - http://www.scopus.com/inward/record.url?scp=0019227991&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019227991&partnerID=8YFLogxK
U2 - 10.1016/S0010-7824(80)80004-7
DO - 10.1016/S0010-7824(80)80004-7
M3 - Article
C2 - 7002442
AN - SCOPUS:0019227991
VL - 22
SP - 249
EP - 257
JO - Contraception
JF - Contraception
SN - 0010-7824
IS - 3
ER -