Plasminogen activator inhibitor 1 and miscarriage after metformin treatment and laparoscopic ovarian drilling in patients with polycystic ovary syndrome

Stefano Palomba, Francesco Orio, Angela Falbo, Tiziana Russo, Achille Tolino, Fulvio Zullo

Research output: Contribution to journalArticlepeer-review

Abstract

In women with polycystic ovary syndrome, metformin administration, not laparoscopic ovarian drilling, reduces plasminogen activator inhibitor 1 (PAI-1) activity. The lack of a decrease in PAI-1 activity is related to a high risk for miscarriage.

Original languageEnglish
Pages (from-to)761-765
Number of pages5
JournalFertility and Sterility
Volume84
Issue number3
DOIs
Publication statusPublished - Sep 2005

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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