Plastic biliary stent occlusion: Factors involved and possible preventive approaches

Gianfranco Donelli, Emilio Guaglianone, Roberta Di Rosa, Fausto Fiocca, Antonio Basoli

Research output: Contribution to journalArticlepeer-review


Endoscopic biliary stenting is today the most common palliative treatment for patients suffering from obstructive jaundice associated with malignant hepatobiliary tumors or benign strictures. However, recurrent jaundice, with or without cholangitis, is a major complication of a biliary endoprosthesis insertion.Thus, stent removal and replacement with a new one frequently occurs as a consequence of device blockage caused by microbial biofilm growth and biliary sludge accumulation in the lumen. Factors and mechanisms involved in plastic stent clogging arising from epidemiological, clinical and experimental data, as well as the possible strategies to prevent biliary stent failure, will be reviewed and discussed.

Original languageEnglish
Pages (from-to)53-60
Number of pages8
JournalClinical Medicine and Research
Issue number1
Publication statusPublished - Mar 2007


  • Biliary stent
  • Cholangitis
  • Endoscopic insertion
  • Microbial biofilm
  • Prevention
  • Stent occlusion

ASJC Scopus subject areas

  • Medicine(all)
  • Community and Home Care


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