Platelet adhesion and aggregation and fibrin formation in flowing blood: A historical contribution by Giulio Bizzozero

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Abstract

At the occasion of the first centennial of Giulio Bizzozero's death, the modern readers' attention is addressed to some ingenious experiments Bizzozero performed in Turin, Italy, around 1880. He discovered and carefully described blood platelet function in flowing conditions and the relationship between platelet adhesion to an artificial surface, aggregation and subsequent fibrin formation and deposition on activated platelet membrane. Bizzozero challenged contemporary concepts involving leukocytes in blood coagulation, but concluded that participation of blood platelets and white cells in fibrin formation was conceivable.

Original languageEnglish
Pages (from-to)85-89
Number of pages5
JournalPlatelets
Volume13
Issue number2
DOIs
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Hematology
  • Cell Biology

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