Platelet adhesiveness and aggregation in combined factor V and factor VIII deficiency and in combined factor VII and factor VIII deficiency

A. Girolami, L. De Marco, F. Fabris, A. Casonato

Research output: Contribution to journalArticlepeer-review

Abstract

Platelet aggregation and adhesiveness were studied in 3 patients with combined factor V and factor VIII deficiency and in 3 patients with combined factor VII and factor VIII deficiency. The first three patients belonged to three different kindreds whereas the second group belonged to the same kindred. Serotonin C 14 uptake and release was also found to be normal in these patients. These studies indicate that platelet function is normal in combined defects of factor VIII. These findings were in agreement with the presence of a normal bleeding time and a normal factor VIII antigen level in all these patients.

Original languageEnglish
Pages (from-to)663-669
Number of pages7
JournalFolia Haematologica
Volume104
Issue number5
Publication statusPublished - 1977

ASJC Scopus subject areas

  • Hematology

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