Platelet aggregating activity in neuraminidase treated human cryoprecipitates: Its correlation with factor VIII related antigen

J. Vermylen, G. De Gaetano, M. B. Donati, M. Verstraete

Research output: Contribution to journalArticle

Abstract

Neuraminidase induced platelet aggregating activity in cryoprecipitates from three normal subjects and from six haemophilia A patients; the effect was not or only slightly seen in cryoprecipitate from two patients with von Willebrand's disease; development of this activity was linked to the presence of factor VIII related antigen. These findings may be of interest for the diagnosis of von Willebrand's disease and suggest a reaction sequence of major importance for human haemostasis.

Original languageEnglish
Pages (from-to)645-650
Number of pages6
JournalBritish Journal of Haematology
Volume26
Issue number4
Publication statusPublished - 1974

ASJC Scopus subject areas

  • Hematology

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