Platelet aggregation and malondialdehyde formation in type IIA hypercholesterolemic patients

Elena Tremoli; Paola Maderna; Marina Sirtori; Cesare R. Sirtori

doi:10.1159/000214290

Platelet aggregation and malondialdehyde formation in type IIA hypercholesterolemic patients

Elena Tremoli, Paola Maderna, Marina Sirtori, Cesare R. Sirtori

Centro Cardiologico Monzino

Research output: Contribution to journal › Article › peer-review

Abstract

Platelet aggregation induced by threshold concentrations of ADP, adrenaline, collagen and Thrombofax® was evaluated in 25 type IIA hypercholesterolemic patients in comparison with 15 control subjects. Malondialdehyde (MDA) formation induced by collagen and thrombin was also studied in a subgroup of 8 patients. In the patient group, irreversible platelet aggregation was induced by significantly lower concentrations of both adrenaline (p

Original language	English
Pages (from-to)	47-53
Number of pages	7
Journal	Pathophysiology of Haemostasis and Thrombosis
Volume	8
Issue number	1
DOIs	https://doi.org/10.1159/000214290
Publication status	Published - 1979

Keywords

Aggregation
Hyperaggregability
Hyperlipoproteinemia type IIA
Malondialdehyde
Platelets

ASJC Scopus subject areas

Hematology
Physiology (medical)

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keywords = "Aggregation, Hyperaggregability, Hyperlipoproteinemia type IIA, Malondialdehyde, Platelets",

author = "Elena Tremoli and Paola Maderna and Marina Sirtori and Sirtori, {Cesare R.}",

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KW - Hyperlipoproteinemia type IIA

KW - Malondialdehyde

KW - Platelets

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Platelet aggregation and malondialdehyde formation in type IIA hypercholesterolemic patients

Abstract

Keywords

ASJC Scopus subject areas

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