Abstract
Platelet aggregation induced by threshold concentrations of ADP, adrenaline, collagen and Thrombofax® was evaluated in 25 type IIA hypercholesterolemic patients in comparison with 15 control subjects. Malondialdehyde (MDA) formation induced by collagen and thrombin was also studied in a subgroup of 8 patients. In the patient group, irreversible platelet aggregation was induced by significantly lower concentrations of both adrenaline (p
| Original language | English |
|---|---|
| Pages (from-to) | 47-53 |
| Number of pages | 7 |
| Journal | Pathophysiology of Haemostasis and Thrombosis |
| Volume | 8 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1979 |
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Keywords
- Aggregation
- Hyperaggregability
- Hyperlipoproteinemia type IIA
- Malondialdehyde
- Platelets
ASJC Scopus subject areas
- Hematology
- Physiology (medical)
Cite this
Platelet aggregation and malondialdehyde formation in type IIA hypercholesterolemic patients. / Tremoli, Elena; Maderna, Paola; Sirtori, Marina; Sirtori, Cesare R.
In: Pathophysiology of Haemostasis and Thrombosis, Vol. 8, No. 1, 1979, p. 47-53.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Platelet aggregation and malondialdehyde formation in type IIA hypercholesterolemic patients
AU - Tremoli, Elena
AU - Maderna, Paola
AU - Sirtori, Marina
AU - Sirtori, Cesare R.
PY - 1979
Y1 - 1979
N2 - Platelet aggregation induced by threshold concentrations of ADP, adrenaline, collagen and Thrombofax® was evaluated in 25 type IIA hypercholesterolemic patients in comparison with 15 control subjects. Malondialdehyde (MDA) formation induced by collagen and thrombin was also studied in a subgroup of 8 patients. In the patient group, irreversible platelet aggregation was induced by significantly lower concentrations of both adrenaline (p
AB - Platelet aggregation induced by threshold concentrations of ADP, adrenaline, collagen and Thrombofax® was evaluated in 25 type IIA hypercholesterolemic patients in comparison with 15 control subjects. Malondialdehyde (MDA) formation induced by collagen and thrombin was also studied in a subgroup of 8 patients. In the patient group, irreversible platelet aggregation was induced by significantly lower concentrations of both adrenaline (p
KW - Aggregation
KW - Hyperaggregability
KW - Hyperlipoproteinemia type IIA
KW - Malondialdehyde
KW - Platelets
UR - http://www.scopus.com/inward/record.url?scp=0018656830&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018656830&partnerID=8YFLogxK
U2 - 10.1159/000214290
DO - 10.1159/000214290
M3 - Article
C2 - 222654
AN - SCOPUS:0018656830
VL - 8
SP - 47
EP - 53
JO - Pathophysiology of Haemostasis and Thrombosis
JF - Pathophysiology of Haemostasis and Thrombosis
SN - 1424-8832
IS - 1
ER -