Abstract
Platelet aggregation induced by threshold concentrations of ADP, adrenaline, collagen and Thrombofax® was evaluated in 25 type IIA hypercholesterolemic patients in comparison with 15 control subjects. Malondialdehyde (MDA) formation induced by collagen and thrombin was also studied in a subgroup of 8 patients. In the patient group, irreversible platelet aggregation was induced by significantly lower concentrations of both adrenaline (p
Original language | English |
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Pages (from-to) | 47-53 |
Number of pages | 7 |
Journal | Pathophysiology of Haemostasis and Thrombosis |
Volume | 8 |
Issue number | 1 |
DOIs | |
Publication status | Published - 1979 |
Keywords
- Aggregation
- Hyperaggregability
- Hyperlipoproteinemia type IIA
- Malondialdehyde
- Platelets
ASJC Scopus subject areas
- Hematology
- Physiology (medical)