Platelet aggregation and malondialdehyde formation in type IIA hypercholesterolemic patients

Elena Tremoli, Paola Maderna, Marina Sirtori, Cesare R. Sirtori

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Platelet aggregation induced by threshold concentrations of ADP, adrenaline, collagen and Thrombofax® was evaluated in 25 type IIA hypercholesterolemic patients in comparison with 15 control subjects. Malondialdehyde (MDA) formation induced by collagen and thrombin was also studied in a subgroup of 8 patients. In the patient group, irreversible platelet aggregation was induced by significantly lower concentrations of both adrenaline (p

Original languageEnglish
Pages (from-to)47-53
Number of pages7
JournalPathophysiology of Haemostasis and Thrombosis
Volume8
Issue number1
DOIs
Publication statusPublished - 1979

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Malondialdehyde
Platelet Aggregation
Epinephrine
Collagen
Thrombin
Adenosine Diphosphate

Keywords

  • Aggregation
  • Hyperaggregability
  • Hyperlipoproteinemia type IIA
  • Malondialdehyde
  • Platelets

ASJC Scopus subject areas

  • Hematology
  • Physiology (medical)

Cite this

Platelet aggregation and malondialdehyde formation in type IIA hypercholesterolemic patients. / Tremoli, Elena; Maderna, Paola; Sirtori, Marina; Sirtori, Cesare R.

In: Pathophysiology of Haemostasis and Thrombosis, Vol. 8, No. 1, 1979, p. 47-53.

Research output: Contribution to journalArticle

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