Platelet aggregation by thrombofax

G. De Gaetano, J. Vermylen, M. Verstraete

Research output: Contribution to journalArticlepeer-review


The aggregating property of a commercial partial thromboplastin (thrombofax) is reported and its mechanism of action discussed. In Born's aggregometer thrombofax provokes a strong platelet aggregation after a latent period. Evidence was obtained that clumping is due to release of endogeneous platelet ADP. In addition, a direct effect of thrombofax on the platelet membrane is suggested. Thrombofax is a stable, reproducible, ready to use reagent for the evaluation of the platelet release reaction. (Journal received: 29th April, 1974)

Original languageEnglish
Pages (from-to)391-398
Number of pages8
JournalActa Universitatis Carolinae Medica
VolumeMono 53-54
Publication statusPublished - 1972

ASJC Scopus subject areas

  • Medicine(all)


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