Iperaggregazione piastrinica indotta da un anticorpo monoclonale anti-piastrine in una paziente con trombocitemia essenziale in età pediatrica.

P. Perutelli; P. Biglino; A. C. Molinari; E. Boeri; P. G. Mori

Iperaggregazione piastrinica indotta da un anticorpo monoclonale anti-piastrine in una paziente con trombocitemia essenziale in età pediatrica.

Translated title of the contribution: Platelet hyperaggregation induced by an antiplatelet monoclonal antibody in a female patient with essential thrombocythemia of childhood

P. Perutelli, P. Biglino, A. C. Molinari, E. Boeri, P. G. Mori

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

Essential thrombocythemia (ET) is a chronic myeloproliferative disease, rarely observed in pediatric age, characterized by a persistently increased platelet count. Abnormalities of platelet function observed in ET patients may be, at least in part, responsible for the thrombohemorrhagic complications. The authors report about a pediatric patient affected by ET, showing an abnormal platelet response following stimulation by anti-platelet monoclonal antibody. Such finding may be attributable to a structural abnormality of the platelet fibrinogen receptor or to post-receptor alterations.

Translated title of the contribution	Platelet hyperaggregation induced by an antiplatelet monoclonal antibody in a female patient with essential thrombocythemia of childhood
Original language	Italian
Pages (from-to)	688-689
Number of pages	2
Journal	Recenti Progressi in Medicina
Volume	83
Issue number	12
Publication status	Published - Dec 1992

ASJC Scopus subject areas

Medicine(all)

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title = "Iperaggregazione piastrinica indotta da un anticorpo monoclonale anti-piastrine in una paziente con trombocitemia essenziale in et{\`a} pediatrica.",

abstract = "Essential thrombocythemia (ET) is a chronic myeloproliferative disease, rarely observed in pediatric age, characterized by a persistently increased platelet count. Abnormalities of platelet function observed in ET patients may be, at least in part, responsible for the thrombohemorrhagic complications. The authors report about a pediatric patient affected by ET, showing an abnormal platelet response following stimulation by anti-platelet monoclonal antibody. Such finding may be attributable to a structural abnormality of the platelet fibrinogen receptor or to post-receptor alterations.",

author = "P. Perutelli and P. Biglino and Molinari, {A. C.} and E. Boeri and Mori, {P. G.}",

year = "1992",

month = dec,

language = "Italian",

volume = "83",

pages = "688--689",

journal = "Recenti Progressi in Medicina",

issn = "0034-1193",

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T1 - Iperaggregazione piastrinica indotta da un anticorpo monoclonale anti-piastrine in una paziente con trombocitemia essenziale in età pediatrica.

AU - Perutelli, P.

AU - Biglino, P.

AU - Molinari, A. C.

AU - Boeri, E.

AU - Mori, P. G.

PY - 1992/12

Y1 - 1992/12

N2 - Essential thrombocythemia (ET) is a chronic myeloproliferative disease, rarely observed in pediatric age, characterized by a persistently increased platelet count. Abnormalities of platelet function observed in ET patients may be, at least in part, responsible for the thrombohemorrhagic complications. The authors report about a pediatric patient affected by ET, showing an abnormal platelet response following stimulation by anti-platelet monoclonal antibody. Such finding may be attributable to a structural abnormality of the platelet fibrinogen receptor or to post-receptor alterations.

AB - Essential thrombocythemia (ET) is a chronic myeloproliferative disease, rarely observed in pediatric age, characterized by a persistently increased platelet count. Abnormalities of platelet function observed in ET patients may be, at least in part, responsible for the thrombohemorrhagic complications. The authors report about a pediatric patient affected by ET, showing an abnormal platelet response following stimulation by anti-platelet monoclonal antibody. Such finding may be attributable to a structural abnormality of the platelet fibrinogen receptor or to post-receptor alterations.

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C2 - 1494708

AN - SCOPUS:0027029044

VL - 83

SP - 688

EP - 689

JO - Recenti Progressi in Medicina

JF - Recenti Progressi in Medicina

SN - 0034-1193

IS - 12

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