Iperaggregazione piastrinica indotta da un anticorpo monoclonale anti-piastrine in una paziente con trombocitemia essenziale in età pediatrica.

Translated title of the contribution: Platelet hyperaggregation induced by an antiplatelet monoclonal antibody in a female patient with essential thrombocythemia of childhood

P. Perutelli, P. Biglino, A. C. Molinari, E. Boeri, P. G. Mori

Research output: Contribution to journalArticlepeer-review

Abstract

Essential thrombocythemia (ET) is a chronic myeloproliferative disease, rarely observed in pediatric age, characterized by a persistently increased platelet count. Abnormalities of platelet function observed in ET patients may be, at least in part, responsible for the thrombohemorrhagic complications. The authors report about a pediatric patient affected by ET, showing an abnormal platelet response following stimulation by anti-platelet monoclonal antibody. Such finding may be attributable to a structural abnormality of the platelet fibrinogen receptor or to post-receptor alterations.

Translated title of the contributionPlatelet hyperaggregation induced by an antiplatelet monoclonal antibody in a female patient with essential thrombocythemia of childhood
Original languageItalian
Pages (from-to)688-689
Number of pages2
JournalRecenti Progressi in Medicina
Volume83
Issue number12
Publication statusPublished - Dec 1992

ASJC Scopus subject areas

  • Medicine(all)

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