Abstract
Essential thrombocythemia (ET) is a chronic myeloproliferative disease, rarely observed in pediatric age, characterized by a persistently increased platelet count. Abnormalities of platelet function observed in ET patients may be, at least in part, responsible for the thrombohemorrhagic complications. The authors report about a pediatric patient affected by ET, showing an abnormal platelet response following stimulation by anti-platelet monoclonal antibody. Such finding may be attributable to a structural abnormality of the platelet fibrinogen receptor or to post-receptor alterations.
Translated title of the contribution | Platelet hyperaggregation induced by an antiplatelet monoclonal antibody in a female patient with essential thrombocythemia of childhood |
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Original language | Italian |
Pages (from-to) | 688-689 |
Number of pages | 2 |
Journal | Recenti Progressi in Medicina |
Volume | 83 |
Issue number | 12 |
Publication status | Published - Dec 1992 |
ASJC Scopus subject areas
- Medicine(all)