Platelets and arachidonic acid metabolism in human and experimental hypercholesterolemia

E. Tremoli, S. Colli, P. Maderna, R. Paoletti

Research output: Contribution to journalArticlepeer-review


The reported platelet alterations support the concept that platelets may be determining factors in the occurrence of the thromboembolic complications and in the development of atheroclerosis in hypercholesterolemia. Such diseases, however, are multifactorial and platelets may directly or via their released products modulate the behavior of other cell systems, such as leucocytes, endothelial and smooth muscle cells. In particular studies on platelet-vessel wall interactions in different vascular beds, such as coronary and cerebral district, will contribute to the understanding of the basic mechanisms of platelet activation in the atherosclerotic disease.

Original languageEnglish
Pages (from-to)333-337
Number of pages5
JournalVasa - Journal of Vascular Diseases
Issue number4
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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