Platelets: New players in the mucosal scenario of inflammatory bowel disease

S. Danese, F. Scaldaferri, A. Papa, R. Pola, M. Sans, G. Gasbarrini, P. Pola, A. Gasbarrini

Research output: Contribution to journalArticlepeer-review

Abstract

Besides their classical haemostatic task, platelets are now recognized as novel cells deeply involved in inflammation. Compelling evidence support their role as active player in mucosal tissue injury that occurs in Crohn's disease and ulcerative colitis. In both forms of inflammatory bowel disease platelets contribute to microvascular endothelial activation and recruitment of inflammatory cells, thus fostering and amplifying mucosal inflammation.

Original languageEnglish
Pages (from-to)193-198
Number of pages6
JournalEuropean Review for Medical and Pharmacological Sciences
Volume8
Issue number5
Publication statusPublished - Sep 2004

Keywords

  • Endothelium
  • Platelets

ASJC Scopus subject areas

  • Pharmacology

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