Platform independent virtual laboratory system: Simulation of gradient elution HPLC

U. Biader Ceipidor, P. Crescenzi, M. De Paoli, S. Ferraro, M. Iannucci, A. Messina, P. Passamonti

Research output: Contribution to journalArticle

Abstract

A replicative/predictive model has been obtained by enhancing consolidated chromatographic knowledge. Such a model has been implemented in Java language to offer a platform-independent tool to support a virtual laboratory approach, both for didactic purposes and for experimental design in research. A description of the model in terms of data organization and basic algorithm is reported, as well as a summary of the program structure and layout. The program has been tested by examining gradient elution HPLC simulations against expected trends and by comparing results with some experimental data already obtained. A beta version of the program is available on request to be used in PC, Macintosh, or UNIX environments supporting Java tools. An MS-Excel97™ sheet is also available for separate algorithm test.

Original languageEnglish
Pages (from-to)148-158
Number of pages11
JournalInternational Journal of Modelling and Simulation
Volume22
Issue number3
Publication statusPublished - 2002

Fingerprint

Virtual Laboratory
High-performance Liquid Chromatography
System Simulation
Gradient
Java
UNIX
Predictive Model
Experimental design
Design of experiments
Layout
Experimental Data
Model
Simulation

Keywords

  • Chemistry
  • Chromatography
  • HPLC
  • Simulation
  • Virtual laboratory

ASJC Scopus subject areas

  • Chemical Health and Safety
  • Hardware and Architecture
  • Software
  • Safety, Risk, Reliability and Quality
  • Modelling and Simulation

Cite this

Ceipidor, U. B., Crescenzi, P., De Paoli, M., Ferraro, S., Iannucci, M., Messina, A., & Passamonti, P. (2002). Platform independent virtual laboratory system: Simulation of gradient elution HPLC. International Journal of Modelling and Simulation, 22(3), 148-158.

Platform independent virtual laboratory system : Simulation of gradient elution HPLC. / Ceipidor, U. Biader; Crescenzi, P.; De Paoli, M.; Ferraro, S.; Iannucci, M.; Messina, A.; Passamonti, P.

In: International Journal of Modelling and Simulation, Vol. 22, No. 3, 2002, p. 148-158.

Research output: Contribution to journalArticle

Ceipidor, UB, Crescenzi, P, De Paoli, M, Ferraro, S, Iannucci, M, Messina, A & Passamonti, P 2002, 'Platform independent virtual laboratory system: Simulation of gradient elution HPLC', International Journal of Modelling and Simulation, vol. 22, no. 3, pp. 148-158.
Ceipidor, U. Biader ; Crescenzi, P. ; De Paoli, M. ; Ferraro, S. ; Iannucci, M. ; Messina, A. ; Passamonti, P. / Platform independent virtual laboratory system : Simulation of gradient elution HPLC. In: International Journal of Modelling and Simulation. 2002 ; Vol. 22, No. 3. pp. 148-158.
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