Pleural epidermoid carcinoma from displaced skin following extrapleural pneumothorax in a patient exposed to asbestos

A. Sapino, A. Cavallo, A. Donna, G. Bussolati

Research output: Contribution to journalArticlepeer-review

Abstract

This report illustrates a rare case of primary epidermoid carcinoma of the pleura in a patient previously treated by artificial extrapleural pneumothorax for active tuberculosis. The patient had also been occupationally exposed to asbestos. Light microscopic examination showed two different lesions: laminar pleural fragments were covered by normal squamous epithelium that was similar in all respects to epidermis, whereas nodular fragments were composed of well-differentiated infiltrating carcinoma. These findings support the hypothesis that the carcinoma arose from normal epidermis seeded in the pleural cavity during multiple air refills to maintain the pneumothorax. A possible interaction between asbestos fibres and chronic inflammation might have potentiated tumour development.

Original languageEnglish
Pages (from-to)173-176
Number of pages4
JournalVirchows Archiv
Volume429
Issue number2-3
Publication statusPublished - 1996

Keywords

  • Asbestos
  • Carcinoma
  • Pleura
  • Pneumothorax

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint

Dive into the research topics of 'Pleural epidermoid carcinoma from displaced skin following extrapleural pneumothorax in a patient exposed to asbestos'. Together they form a unique fingerprint.

Cite this