Pleural liquid pressure in the zone of apposition and in the lung zone

E. Agostoni, P. G. Agostoni, L. Zocchi

Research output: Contribution to journalArticle

Abstract

Pleural liquid pressure in zone of apposition (Pliq,ap) and in lung zone (Pliq, l) was measured simultaneously through liquid filled cannulas in anesthetized dogs in lateral posture. At top Pliq,ap and Pliq,l at iso-height were -9.7 ± 0.4 and -11.9 ± 0.3 cmH2O, respectively, at the end expiration (ee; P of Δ <0.01; 11 dogs); -9.6 ± 0.7 and -19.8 ± 0.7 cm H2O at end inspiration (ei). At bottom they were -0.6 ± 0.2 and -2.4 ± 0.4 cm H2O, respectively, at ee (P of Δ <0.05; 4 dogs); -1.5 ± 0.3 and -8.5 ± 1.0 cm H2O at ei. Vertical gradient of Pliq,ap was -0.97 ± 0.02 cm H2O/cm. A 132% increase in ventilation (after 10 min dead space breathing) did not change ee and ei Pliq,ap, and ee Pliq,l, but decreased ei Pliq,l. These results imply: (1) no transmission to zone of apposition of tidal changes in Pliq,l; (2) a liquid flow from zone of apposition to lung zone; (3) a net filtration into zone of apposition. They suggest that absorption pressure of capillaries of visceral pleura is greater than that of lymphatics of zone of apposition. Lymphatic role in setting Pliq,l is discussed.

Original languageEnglish
Pages (from-to)357-370
Number of pages14
JournalRespiration Physiology
Volume75
Issue number3
DOIs
Publication statusPublished - 1989

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Dogs
Pressure
Lung
Pleura
Posture
Ventilation
Respiration
Cannula

Keywords

  • Deformation pressure
  • Dog
  • Exchange of pleural liquid
  • Vertical gradient of liquid pressure

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine

Cite this

Pleural liquid pressure in the zone of apposition and in the lung zone. / Agostoni, E.; Agostoni, P. G.; Zocchi, L.

In: Respiration Physiology, Vol. 75, No. 3, 1989, p. 357-370.

Research output: Contribution to journalArticle

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abstract = "Pleural liquid pressure in zone of apposition (Pliq,ap) and in lung zone (Pliq, l) was measured simultaneously through liquid filled cannulas in anesthetized dogs in lateral posture. At top Pliq,ap and Pliq,l at iso-height were -9.7 ± 0.4 and -11.9 ± 0.3 cmH2O, respectively, at the end expiration (ee; P of Δ <0.01; 11 dogs); -9.6 ± 0.7 and -19.8 ± 0.7 cm H2O at end inspiration (ei). At bottom they were -0.6 ± 0.2 and -2.4 ± 0.4 cm H2O, respectively, at ee (P of Δ <0.05; 4 dogs); -1.5 ± 0.3 and -8.5 ± 1.0 cm H2O at ei. Vertical gradient of Pliq,ap was -0.97 ± 0.02 cm H2O/cm. A 132{\%} increase in ventilation (after 10 min dead space breathing) did not change ee and ei Pliq,ap, and ee Pliq,l, but decreased ei Pliq,l. These results imply: (1) no transmission to zone of apposition of tidal changes in Pliq,l; (2) a liquid flow from zone of apposition to lung zone; (3) a net filtration into zone of apposition. They suggest that absorption pressure of capillaries of visceral pleura is greater than that of lymphatics of zone of apposition. Lymphatic role in setting Pliq,l is discussed.",
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