pO2 measurement in an experimental model of patellar tendon autograft pro-anterior cruciate ligament

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Abstract

Thirty-four sheep were submitted to surgery substituting the native ACL with the central third of the patellar tendon, ten enter this study. The purpose was to find a possible relationship between tissue pO2 and healing processes considering also the biomechanical and histomorphological aspects of the grafts. Four of them were sacrificed under general anaesthesia after 6 months, and six after 1 year in order to perform tissue pO2 measurement and an analysis of microvessel density on specimens of the normal ACL and the graft. Our data showed higher pO2 values of the autografts after 6 months. After 1 year the data was comparable to those of native ACL. This was confirmed by a microvessel count of the histological specimens and the data was in relationship to biomechanical and histomorphological analysis. Tissue pO2 can be observed and recorded in 'in vivo' ACL, and patellar tendon used as graft, with no injury to their integrity. The monitoring system might be considered as an experimental tool for indirect controls of the anterior cruciate substitutes.

Original languageEnglish
Pages (from-to)174-178
Number of pages5
JournalInternational Journal of Artificial Organs
Volume21
Issue number3
Publication statusPublished - 1998

Keywords

  • ACL
  • Patellar tendon
  • pO

ASJC Scopus subject areas

  • Biophysics

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