POLG1 in idiopathic Parkinson disease

W. Tiangyou, G. Hudson, D. Ghezzi, G. Ferrari, M. Zeviani, D. J. Burn, P. F. Chinnery

Research output: Contribution to journalArticle

Abstract

We studied POLG1 in 140 UK patients with idiopathic Parkinson disease (PD) and 279 Italian patients with PD and compared them to a UK control group (n = 207) and an Italian control group (n = 285). Our observations do not support a role for common POLG1 genetic variants in PD and indicate that dominant POLG1 mutations are a rare cause of parkinsonism in the general population.

Original languageEnglish
Pages (from-to)1698-1700
Number of pages3
JournalNeurology
Volume67
Issue number9
DOIs
Publication statusPublished - Nov 2006

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'POLG1 in idiopathic Parkinson disease'. Together they form a unique fingerprint.

  • Cite this

    Tiangyou, W., Hudson, G., Ghezzi, D., Ferrari, G., Zeviani, M., Burn, D. J., & Chinnery, P. F. (2006). POLG1 in idiopathic Parkinson disease. Neurology, 67(9), 1698-1700. https://doi.org/10.1212/01.wnl.0000238963.07425.d5