POLG1 in idiopathic Parkinson disease

W. Tiangyou, G. Hudson, D. Ghezzi, G. Ferrari, M. Zeviani, D. J. Burn, P. F. Chinnery

Research output: Contribution to journalArticlepeer-review


We studied POLG1 in 140 UK patients with idiopathic Parkinson disease (PD) and 279 Italian patients with PD and compared them to a UK control group (n = 207) and an Italian control group (n = 285). Our observations do not support a role for common POLG1 genetic variants in PD and indicate that dominant POLG1 mutations are a rare cause of parkinsonism in the general population.

Original languageEnglish
Pages (from-to)1698-1700
Number of pages3
Issue number9
Publication statusPublished - Nov 2006

ASJC Scopus subject areas

  • Neuroscience(all)


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