POLG1 in idiopathic Parkinson disease

W. Tiangyou, G. Hudson, D. Ghezzi, G. Ferrari, M. Zeviani, D. J. Burn, P. F. Chinnery

Research output: Contribution to journalArticle

Abstract

We studied POLG1 in 140 UK patients with idiopathic Parkinson disease (PD) and 279 Italian patients with PD and compared them to a UK control group (n = 207) and an Italian control group (n = 285). Our observations do not support a role for common POLG1 genetic variants in PD and indicate that dominant POLG1 mutations are a rare cause of parkinsonism in the general population.

Original languageEnglish
Pages (from-to)1698-1700
Number of pages3
JournalNeurology
Volume67
Issue number9
DOIs
Publication statusPublished - Nov 2006

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Parkinson Disease
Control Groups
Parkinsonian Disorders
Mutation
Population

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Tiangyou, W., Hudson, G., Ghezzi, D., Ferrari, G., Zeviani, M., Burn, D. J., & Chinnery, P. F. (2006). POLG1 in idiopathic Parkinson disease. Neurology, 67(9), 1698-1700. https://doi.org/10.1212/01.wnl.0000238963.07425.d5

POLG1 in idiopathic Parkinson disease. / Tiangyou, W.; Hudson, G.; Ghezzi, D.; Ferrari, G.; Zeviani, M.; Burn, D. J.; Chinnery, P. F.

In: Neurology, Vol. 67, No. 9, 11.2006, p. 1698-1700.

Research output: Contribution to journalArticle

Tiangyou, W, Hudson, G, Ghezzi, D, Ferrari, G, Zeviani, M, Burn, DJ & Chinnery, PF 2006, 'POLG1 in idiopathic Parkinson disease', Neurology, vol. 67, no. 9, pp. 1698-1700. https://doi.org/10.1212/01.wnl.0000238963.07425.d5
Tiangyou W, Hudson G, Ghezzi D, Ferrari G, Zeviani M, Burn DJ et al. POLG1 in idiopathic Parkinson disease. Neurology. 2006 Nov;67(9):1698-1700. https://doi.org/10.1212/01.wnl.0000238963.07425.d5
Tiangyou, W. ; Hudson, G. ; Ghezzi, D. ; Ferrari, G. ; Zeviani, M. ; Burn, D. J. ; Chinnery, P. F. / POLG1 in idiopathic Parkinson disease. In: Neurology. 2006 ; Vol. 67, No. 9. pp. 1698-1700.
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