TY - JOUR
T1 - Polyclonal serum-free light chains elevation in HIV-infected patients
AU - Bibas, Michele
AU - Lorenzini, Patrizia
AU - Cozzi-Lepri, Alessandro
AU - Calcagno, Andrea
AU - Di Giambenedetto, Simona
AU - Costantini, Andrea
AU - Castagna, Antonella
AU - Manfrin, Vinicio
AU - Monforte, Antonella D.
AU - Antinori, Andrea
PY - 2012/10/23
Y1 - 2012/10/23
N2 - We investigated the association between polyclonal serum-free light chains and prognostic biomarkers routinely used in the setting of HIV infection. For this purpose serum samples of 182 HIV-infected patients from the Italian Cohort of Antiretroviral Naive Patients foundation cohort were analysed. We found that polyclonal serum free light chains above the upper normal limit are strongly correlated in HIV-infected patients with advancing age, shorter time of undetectable HIV viremia, higher viral load and with lower CD4 cell count at sample.
AB - We investigated the association between polyclonal serum-free light chains and prognostic biomarkers routinely used in the setting of HIV infection. For this purpose serum samples of 182 HIV-infected patients from the Italian Cohort of Antiretroviral Naive Patients foundation cohort were analysed. We found that polyclonal serum free light chains above the upper normal limit are strongly correlated in HIV-infected patients with advancing age, shorter time of undetectable HIV viremia, higher viral load and with lower CD4 cell count at sample.
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U2 - 10.1097/QAD.0b013e328358d54b
DO - 10.1097/QAD.0b013e328358d54b
M3 - Article
C2 - 22874521
AN - SCOPUS:84867744620
VL - 26
SP - 2107
EP - 2110
JO - AIDS
JF - AIDS
SN - 0269-9370
IS - 16
ER -