Polyclonal serum-free light chains elevation in HIV-infected patients

Michele Bibas, Patrizia Lorenzini, Alessandro Cozzi-Lepri, Andrea Calcagno, Simona Di Giambenedetto, Andrea Costantini, Antonella Castagna, Vinicio Manfrin, Antonella D. Monforte, Andrea Antinori

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated the association between polyclonal serum-free light chains and prognostic biomarkers routinely used in the setting of HIV infection. For this purpose serum samples of 182 HIV-infected patients from the Italian Cohort of Antiretroviral Naive Patients foundation cohort were analysed. We found that polyclonal serum free light chains above the upper normal limit are strongly correlated in HIV-infected patients with advancing age, shorter time of undetectable HIV viremia, higher viral load and with lower CD4 cell count at sample.

Original languageEnglish
Pages (from-to)2107-2110
Number of pages4
JournalAIDS (London, England)
Volume26
Issue number16
DOIs
Publication statusPublished - Oct 23 2012

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

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