TY - JOUR
T1 - Polyflex stents for malignant oesophageal and oesophagogastric stricture
T2 - A prospective, multicentric study
AU - Conigliaro, Rita
AU - Battaglia, Giorgio
AU - Repici, Alessandro
AU - De Pretis, Giovanni
AU - Ghezzo, Luigi
AU - Bittinger, Max
AU - Messmann, Helmut
AU - Demarquay, Jean François
AU - Togni, Michele
AU - Blanchi, Sabrina
AU - Filiberti, Rosangela
AU - Conio, Massimo
PY - 2007/3
Y1 - 2007/3
N2 - OBJECTIVE: Dysphagia is the most distressing symptom in patients with cancer-related oesophageal obstruction. Endoscopic palliation aims to restore swallowing, avoid reintervention and to reduce hospitalization. This study reports an experience with a new self-expandable plastic stent (Polyflex) in patients with unresectable oesophageal and oesophagogastric junction cancer. METHODS: Sixty patients were prospectively collected. The cause of obstruction was oesophageal squamous cell carcinoma (44) and adenocarcinoma (eight), lung cancer (seven) and thyroid tumour (one). RESULTS: The stent was successfully placed in 59 patients. Early minor complications occurred in 19 patients (32%), and major complications in 13 (22%). Death occurred in three patients owing to pulmonary embolism (one) and massive haemorrhage (two). Recurrent dysphagia for early stent migration was observed in seven patients. Delayed stent migration occurred in five patients and tumour overgrowth in eight patients. The mean dysphagia score of 2.8 improved to a mean score of 1.0 after stenting (P
AB - OBJECTIVE: Dysphagia is the most distressing symptom in patients with cancer-related oesophageal obstruction. Endoscopic palliation aims to restore swallowing, avoid reintervention and to reduce hospitalization. This study reports an experience with a new self-expandable plastic stent (Polyflex) in patients with unresectable oesophageal and oesophagogastric junction cancer. METHODS: Sixty patients were prospectively collected. The cause of obstruction was oesophageal squamous cell carcinoma (44) and adenocarcinoma (eight), lung cancer (seven) and thyroid tumour (one). RESULTS: The stent was successfully placed in 59 patients. Early minor complications occurred in 19 patients (32%), and major complications in 13 (22%). Death occurred in three patients owing to pulmonary embolism (one) and massive haemorrhage (two). Recurrent dysphagia for early stent migration was observed in seven patients. Delayed stent migration occurred in five patients and tumour overgrowth in eight patients. The mean dysphagia score of 2.8 improved to a mean score of 1.0 after stenting (P
KW - Cancer
KW - Dysphagia
KW - Oesophagus
KW - Plastic stent
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U2 - 10.1097/MEG.0b013e328013a418
DO - 10.1097/MEG.0b013e328013a418
M3 - Article
C2 - 17301645
AN - SCOPUS:33847011769
VL - 19
SP - 195
EP - 203
JO - European Journal of Gastroenterology and Hepatology
JF - European Journal of Gastroenterology and Hepatology
SN - 0954-691X
IS - 3
ER -