Polyflex stents for malignant oesophageal and oesophagogastric stricture: A prospective, multicentric study

Rita Conigliaro, Giorgio Battaglia, Alessandro Repici, Giovanni De Pretis, Luigi Ghezzo, Max Bittinger, Helmut Messmann, Jean François Demarquay, Michele Togni, Sabrina Blanchi, Rosangela Filiberti, Massimo Conio

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: Dysphagia is the most distressing symptom in patients with cancer-related oesophageal obstruction. Endoscopic palliation aims to restore swallowing, avoid reintervention and to reduce hospitalization. This study reports an experience with a new self-expandable plastic stent (Polyflex) in patients with unresectable oesophageal and oesophagogastric junction cancer. METHODS: Sixty patients were prospectively collected. The cause of obstruction was oesophageal squamous cell carcinoma (44) and adenocarcinoma (eight), lung cancer (seven) and thyroid tumour (one). RESULTS: The stent was successfully placed in 59 patients. Early minor complications occurred in 19 patients (32%), and major complications in 13 (22%). Death occurred in three patients owing to pulmonary embolism (one) and massive haemorrhage (two). Recurrent dysphagia for early stent migration was observed in seven patients. Delayed stent migration occurred in five patients and tumour overgrowth in eight patients. The mean dysphagia score of 2.8 improved to a mean score of 1.0 after stenting (P

Original languageEnglish
Pages (from-to)195-203
Number of pages9
JournalEuropean Journal of Gastroenterology and Hepatology
Volume19
Issue number3
DOIs
Publication statusPublished - Mar 2007

Keywords

  • Cancer
  • Dysphagia
  • Oesophagus
  • Plastic stent

ASJC Scopus subject areas

  • Gastroenterology

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