Polymorphisms in TREX1 and susceptibility to HIV-1 infection

A. Pontillo, M. Girardelli, E. Catamo, A. J. Duarte, S. Crovella

Research output: Contribution to journalArticlepeer-review


Summary: TREX-1 is a restriction factor against HIV-1. The coding sequence of TREX1 gene was analysed in HIV+ subjects searching for genetic variations possibly associated with the susceptibility to HIV infection. The single nucleotide polymorphism rs3135945 was significantly associated with HIV infection, emphasizing the involvement of TREX-1 in the anti-HIV response.

Original languageEnglish
Pages (from-to)492-494
Number of pages3
JournalInternational Journal of Immunogenetics
Issue number6
Publication statusPublished - Dec 2013

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Immunology
  • Genetics(clinical)

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